Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder

NCT07134569 | Recruiting

• 1 other identifier: 202311005RINC
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in individuals with autism, and verifying whether motor training can effectively improve muscle strength, balance, and motor control. The main questions aim to answer are: \[primary hypothesis or outcome measure 1\]? \[primary hypothesis or outcome measure 2\]? If there is a comparison group: Researchers will compare \[arm information\] to see if \[insert effects\]. Participants will \[describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items\].

Conditions

Autism

Keywords

Virtual Reality; motor training

Outcome Measures

Primary Outcomes (2)

• The performance of movement operational assessment

  Participants will take movement operational assessment, which composed of different tests, such as Timed Up and Go Test (TUG), the 10-meter walk test (10MWT) and the 6-minute walk test (6WMT)

  40 minutes

• The performance of motor coordination control

  the performance recorded with Vicon, an motion capture system, and Single Leg Stance Test

  1 hour, twice

Secondary Outcomes (4)

• The N-back Task performance

  40 minutes

• The performance of Timed Up and Go Test (TUG)

  1 minute, twice

• The performance of the 10-meter walk test (10MWT)

  1 minute, twice

• The performance of 6-minute walk test (6WMT)

  6 minutes, twice

Study Arms (2)

Autism

EXPERIMENTAL

Behavioral: VR-based motor training

Typically developing control

NO INTERVENTION

Interventions

VR-based motor training BEHAVIORAL

Six weeks, twice per week.

Autism

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• young adult aged between 18 and 45 years who had a diagnosis of ASD from a licensed mental health or medical professional based on DSM-5.
• was motivated to complete the 6-week VR-based motor function training.
• had a full-scale IQ \> 70 on the WAIS-IV.

You may not qualify if:

• a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury) that hamper walking function, or neurosurgery.
• visual impairment and/or hearing impairment that would preclude participation in motor assessment or training.
• The Non-ASD control group
• young adult aged between 18 and 45 years who do not have a diagnosis of ASD.
• had a full-scale IQ \> 70 on the WAIS-IV.
• a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis), neurological diseases (e.g., stroke, lumbar radiculopathy, or spinal cord injury), or neurosurgery that hamper walking function.
• visual impairment and/or hearing impairment that would preclude participation in motor assessment or training.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan

RECRUITING

MeSH Terms

Conditions

Autistic Disorder

Condition Hierarchy (Ancestors)

Autism Spectrum Disorder; Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Central Study Contacts

Yi Ling Chien, Clinical Professor

CONTACT

+886 2-23123456; ntuh.peers@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 4, 2025
• First Posted: August 21, 2025
• Study Start: December 15, 2023
• Primary Completion (Estimated): July 31, 2027
• Study Completion (Estimated): July 31, 2027
• Last Updated: January 12, 2026

Record last verified: 2025-12

Locations

TW (1)