Central Sensitization Presence on the Results of Shoulder Adhesive Capsulitis

NCT07131839 | Completed

• 2 other identifiers: KA 21/47AnkaraCHBilkent
• Study Type: observational
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Patients with adhesive capulitis longlasting more than 3 months were participated in the study. they were divided into two groups whether they have central sensitizaiton or not. Conventional physical therapy responses were measured and compared between two groups.

Conditions

Adhesive Capsulitis of the Shoulder

Keywords

Adhesive Capsulitis; chronic pain

Outcome Measures

Primary Outcomes (3)

• Visual Analog Scale

  A 10 cm VAS, with known validity and reliability, was used as a self-reported measure for the severity of joint pain.

  at baseline (T0), after treatment (T1) and at 2nd week after completion of conventional rehabilitation program (T2)

• Shoulder Pain Disability Index (SPADI)

  This questionnaire was developed to assess shoulder joint pain and disability. The SPADI has two sections; first section contains 5 questions to evaluate pain, whereas second item contains 8 questions to evaluate disability. Scores vary 0-130 and higher scores indicates high disability rates and pain

  at baseline (T0), after treatment (T1) and at 2nd week after completion of conventional rehabilitation program (T2)

• Measurement of Shoulder range of motion

  The same physician performed the measurement for the joint ranges in each plane of the joint with a goniometer. The goniometer's pivot point was positioned on the lateral projection of the shoulder joint while subjects in supine position. The fixed arm aligned parallel to the axillary lateral midline , while the movable arm tracked the humerus' lateral midline movement towards the axilla. The joint was passively forced to the end of the direction of range and measured twice and the average was taken

  at baseline (T0), after treatment (T1) and at 2nd week after completion of conventional rehabilitation program (T2)

Secondary Outcomes (3)

• Tampa Kinesiophobia Scale (TKS)

  at baseline (T0), after treatment (T1) and at 2nd week after completion of conventional rehabilitation program (T2)

• Pain Catastrophizing Scale (PCS)

  at baseline (T0), after treatment (T1) and at 2nd week after completion of conventional rehabilitation program (T2).

• Beck Depression Inventory (BDI)

  at baseline (T0), after treatment (T1) and at 2nd week after completion of conventional rehabilitation program (T2)

Study Arms (2)

Group 1

Adhesive shoulder patients with central sensitization

Group 2

Adhesive capsulitis patients without central sensitization

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adhesive capsulitis patients aged between 18-80 years, and symptoms ongoing more than 3 months were participated in the study

You may qualify if:

• )patients with adhesive capsulitis between 18-80 years old 2) symptoms ongoing more than 3 months 3) willing to participated in the study

You may not qualify if:

• \) patients with cervical radiculopathy 2) Patients with predisposing factors to adhesive capsulitis, such as diabetes mellitus, thyroid disease, coronary artery disease, lung pathologies or tuberculosis 3) any defined central sensitization syndrome such as fibromiyalgia before 4) presence of rheumatologic diseases 5) pregnancy 6) patients underwent bypass surgery or who have cardiac pacemaker 7) patients with septic arthritis or sepsis 8) malignancy 9) patients that underwent surgery through the shoulder region or had injection through the shoulder joint in the last 3 months.

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)

Location

Related Publications (3)

• Bilika P, Nijs J, Fandridis E, Dimitriadis Z, Strimpakos N, Kapreli E. In the Shoulder or in the Brain? Behavioral, Psychosocial and Cognitive Characteristics of Unilateral Chronic Shoulder Pain with Symptoms of Central Sensitization. Healthcare (Basel). 2022 Aug 30;10(9):1658. doi: 10.3390/healthcare10091658.

  PMID: 36141270 BACKGROUND

• Brindisino F, Girardi G, Crestani M, Fiore A, Giovannico G, Garzonio F, Venturin D, Struyf F. Effectiveness of electrophysical agents in subjects with frozen shoulder: a systematic review and meta-analysis. Disabil Rehabil. 2024 Aug;46(16):3513-3534. doi: 10.1080/09638288.2023.2251880. Epub 2023 Sep 5.

  PMID: 37667875 BACKGROUND

• James-Belin E, Lasbleiz S, Haddad A, Morchoisne O, Ostertag A, Yelnik A, Laredo JD, Bardin T, Orcel P, Richette P, Beaudreuil J. Shoulder adhesive capsulitis: diagnostic value of active and passive range of motion with volume of gleno-humeral capsule as a reference. Eur J Phys Rehabil Med. 2020 Aug;56(4):438-443. doi: 10.23736/S1973-9087.19.05890-8. Epub 2019 Nov 18.

  PMID: 31742369 BACKGROUND

MeSH Terms

Conditions

Bursitis; Chronic Pain

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Prof

Study Record Dates

• First Submitted: August 13, 2025
• First Posted: August 20, 2025
• Study Start: January 1, 2021
• Primary Completion: June 1, 2022
• Study Completion: June 1, 2022
• Last Updated: August 20, 2025

Record last verified: 2025-08

Locations

TU (1)