Assessment of Diaphragmatic Mobility in Dyspneic Patients With Different Types of Interstitial Lung Diseases

NCT07131072 | Completed

• 1 other identifier: FMASU R13/2021
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

dyspnea and impaired exercise capacity in IPF patients can be related, at least in part, to respiratory muscle dysfunction, in particular to diaphragm functionality. Both B-mode and M-mode ultrasound techniques have been employed to assess diaphragm excursion, which measures the distance that the diaphragm is able to move during the respiratory cycle. recent study using lung ultrasound in assessment of diaphragmatic mobility in IPF patients and found that Diaphragmatic mobility is lower in IPF patients than in healthy controls, especially during deep inspiration. The correlation between reduced FVC and diaphragmatic excursion values in IPF patients can be of interest, since it could represent an index of functional respiratory affection performed by chest ultrasound

Conditions

Diaphragm Issues

Outcome Measures

Primary Outcomes (1)

• diaphragm mobility assessment in different types of interstitial lung diseases

  measurement of diaphragmatic excursion in cm in different types of interstitial lung diseases

  1 year

Secondary Outcomes (1)

• Correlation between diaphragmatic mobility and functional assessment in different ILD types

  1 year

Study Arms (3)

collagen related interstitial lung disease

Other: daiphragm mobility by ultrsound; Other: spirometry ,DLCo

idiopathic type (IPF)

Other: daiphragm mobility by ultrsound; Other: spirometry ,DLCo

OTHERS(occupational,sarcoid,...)

Other: daiphragm mobility by ultrsound; Other: spirometry ,DLCo

Interventions

daiphragm mobility by ultrsound OTHER

fibrosis score, alveolitis score by CT Chest

Also known as: warricks score

OTHERS(occupational,sarcoid,...); collagen related interstitial lung disease; idiopathic type (IPF)

spirometry ,DLCo OTHER

FEV1, FVC, FEV1/FVC, DLCo

OTHERS(occupational,sarcoid,...); collagen related interstitial lung disease; idiopathic type (IPF)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients presented to Ain Shams University Hospital's chest outpatient clinic by ILD due to any cause with age more than 18 years

You may qualify if:

• patients presented to Ain Shams University Hospital outpatient clinic by ILD due to any cause

You may not qualify if:

• Pregnant females
• Patients with end stage organ failure e.g.: Renal failure, liver cell failure
• Patients with malignancy elsewhere.
• The patients who refuse to be entitled in the study.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams university

Cairo, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: August 6, 2025
• First Posted: August 20, 2025
• Study Start: February 1, 2021
• Primary Completion: September 1, 2022
• Study Completion: June 1, 2025
• Last Updated: August 24, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)