NCT07127887

Brief Summary

Knowledge mobilization (KM) resources are tools designed to facilitate the use of research evidence in healthcare decision-making. These resources are created in various formats - including plain language summaries, infographics, and videos - to meet the needs of diverse end-users, such as healthcare professionals, policymakers, patients, and caregivers. They are intended to be easily accessible; however, individuals whose first language is not English may have difficulty understanding them. Thus, translating KM resources into other languages is essential to support health equity and accessibility, but it is often costly and time intensive. This study aims to explore whether artificial intelligence (AI) tools, specifically ChatGPT - an AI-based large language model developed by OpenAI - can effectively translate KM resources for members of the public whose first language is not English. The resource being evaluated offers guidance on preventing post-COVID-19 condition and has already been translated by a professional (human) translator into seven languages commonly spoken in Canada: French, Spanish, Ukrainian, Tagalog, Arabic, Chinese, and Punjabi. Using ChatGPT, AI-generated translations will be created in those same seven languages. For this study, participants - adults living in Canada whose first language is one of the selected languages and able to read English - will be randomly assigned to review either an AI-generated or a professionally translated version of a KM resource. They will then complete a questionnaire evaluating their understanding of the resource, as well as the readability and acceptability of the translation. This study will contribute to the Investigators' understanding of the potential use of AI for translating health information. The goal is to support equitable access to health information and promote citizen-centered care by reducing language barriers using innovative solutions.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
350

participants targeted

Target at P75+ for not_applicable

Timeline
9mo left

Started Jul 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress51%
Jul 2025Jan 2027

Study Start

First participant enrolled

July 28, 2025

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

August 6, 2025

Completed
11 days until next milestone

First Posted

Study publicly available on registry

August 17, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 22, 2025

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2027

Expected
Last Updated

February 9, 2026

Status Verified

February 1, 2026

Enrollment Period

4 months

First QC Date

August 6, 2025

Last Update Submit

February 4, 2026

Conditions

Keywords

Knowledge mobilizationArtificial intelligenceLinguistic translationCultural diversityChat GPTHealth Equity

Outcome Measures

Primary Outcomes (1)

  • Understanding

    Measured by participant responses to a set of 7 multiple-choice questions specifically designed to evaluate key content knowledge about post COVID-19 condition and related recommendations contained in the resource. The number of correct answers will serve as an objective indicator of understanding, assessing the ability of each translation method to preserve critical concepts.

    Baseline

Secondary Outcomes (2)

  • Readability

    Baseline

  • Acceptability

    Baseline

Study Arms (2)

Group A - AI

EXPERIMENTAL

ChatGPT

Other: KM Resource - AI

Group B - Professional

EXPERIMENTAL

Human translator

Other: KM Resource - Professional

Interventions

The KM resource (an online resource sheet) was developed for the Public Health Agency of Canada about the prevention of post-covid condition (PCC). The resource presents recommendations that were developed by an international group according to standards for guideline development. The resource has already been AI translated using ChatGPT 4.0 into French as well as six languages common to newcomers across Canada (Arabic, Punjabi, Ukrainian, Tagalog, Chinese, Spanish).

Group A - AI

The KM resource (an online resource sheet) was developed for the Public Health Agency of Canada about the prevention of post-covid condition (PCC). The resource presents recommendations that were developed by an international group according to standards for guideline development. The resource has already been professionally translated into French as well as six languages common to newcomers across Canada (Arabic, Punjabi, Ukrainian, Tagalog, Chinese, Spanish).

Group B - Professional

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • 18 years of age or older
  • Living in Canada
  • First language is one of the selected languages (i.e. French, Spanish, Ukrainian, Tagalog, Arabic, Chinese, and Punjabi)
  • Able to read and complete a questionnaire in English
  • Access to an electronic device (e.g. computer or tablet), Internet and email

You may not qualify if:

  • Under the age of 18 years
  • Does not live in Canada
  • First language is not one of the selected languages (i.e. French, Spanish, Ukrainian, Tagalog, Arabic, Chinese, and Punjabi)
  • Unable to read and complete a questionnaire in English
  • No access to an electronic device (e.g. computer or tablet), Internet or email

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Alberta

Edmonton, Alberta, T5K2H6, Canada

RECRUITING

Study Officials

  • Lisa Hartling, PhD

    University of Alberta

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sarah A Elliott, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
Participants will be blinded to the type of translation they receive. They will be informed that the study compares different translation methods but will not be told whether the materials they view were translated by AI or by professional translators.
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned (1:1 allocation ratio) to receive either an AI-translated version or a professionally translated version of a KM resource.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 6, 2025

First Posted

August 17, 2025

Study Start

July 28, 2025

Primary Completion

November 22, 2025

Study Completion (Estimated)

January 31, 2027

Last Updated

February 9, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations