NCT04247529

Brief Summary

Many population-level public health strategies-including media campaigns and other behavioral interventions, screening recommendations, and vaccination policies-rely on messaging to promote cancer prevention and control. These strategies do not take place in a vacuum; rather, they occur in the context of a broader public information environment, which is increasingly characterized by conflicting and often controversial health information. Although studies have documented that such information is prevalent, a critical question remains unanswered: does exposure to conflicting health information in people's routine interactions with the broader information environment threaten the success of message-based population-level public health strategies? And, if so, who is most susceptible to the effects of such exposure? This study will provide a rigorous empirical test of these critical answered questions, guided by two specific aims: First, to evaluate whether prior exposure to conflicting health information influences responses to subsequent unrelated and uncontested health messages, a phenomenon that has been described as "carryover effects" (Primary Aim); and second, to identify whether there are individual-level differences in how conflict affects responses to these unrelated and uncontested health messages (Secondary Aim).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6,046

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 16, 2020

Completed
14 days until next milestone

First Posted

Study publicly available on registry

January 30, 2020

Completed
6 months until next milestone

Study Start

First participant enrolled

July 20, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2020

Completed
Last Updated

November 10, 2020

Status Verified

November 1, 2020

Enrollment Period

1 month

First QC Date

January 16, 2020

Last Update Submit

November 9, 2020

Conditions

Outcome Measures

Primary Outcomes (6)

  • Negative affective responses

    * Participants are asked to indicate how "the ad you just saw made you feel" * 7 affective responses are randomly ordered: interested, frustrated, surprised, annoyed, distressed, optimistic, worried (response options: 1 "very slightly or not at all" to 5 "extremely")

    Up to 42 days

  • Counterarguing

    • Participants are asked to indicate the extent to which they agree or disagree with 4 statements (randomly ordered; response options: 1 "strongly disagree" to 5 "strongly agree"): * "I found myself agreeing with the ad" (reverse coded) * "I thought of points that went against what the ad was saying" * "I accepted the ad's claims" (reverse coded) * "While reading the ad, I was skeptical of its claims"

    Up to 42 days

  • Reactance/threat to freedom

    • Participants are asked to indicate the extent to which they agree or disagree with the following statement (response options: 1 "strongly disagree" to 5 "strongly agree"): "I felt like the ad was trying to manipulate me"

    Up to 42 days

  • Other negative cognitive responses to ad claims

    • Participants are asked to indicate whether "the claims in the ad I just saw are" (randomly ordered; response options: 1 "strongly disagree" to 5 "strongly agree"): exaggerated, flawed, believable (reverse coded), reasonable (reverse coded)

    Up to 42 days

  • Perceived argument strength

    • Participants are asked to indicate the extent to which they agree or disagree with 2 statements (randomly ordered; response options: 1 "strongly disagree" to 5 "strongly agree"): * "The ad was convincing" * "The ad gave me a strong reason to \[engage in the behavior specified in the ad\]"

    Up to 42 days

  • Response efficacy

    • Participants are asked to respond to two items, presented in random order: * "How confident are you that there is evidence to support the ad's claims?" (1 "not confident at all" to 7 "extremely confident") * "How much do you think your health would benefit if you \[engaged in the behavior specified in the ad\]?" (1 "not at all" to 7 "extremely")

    Up to 42 days

Study Arms (2)

No exposure to conflict

PLACEBO COMPARATOR
Other: No exposure to conflicting health information

Exposure to conflict

EXPERIMENTAL
Other: Exposure to conflicting health information

Interventions

At 2 time points across a \~28-day period, participants will be exposed to news stories and social media posts about 6 health topics: mammography screening, prostate-specific antigen (PSA) testing, Vitamin D supplementation, carbohydrate consumption, alcohol consumption, and breastfeeding. Participants in the conflict (experimental) group will have conflicting information added to these news and social media posts.

Exposure to conflict

At 2 time points across a \~28-day period, participants will be exposed to news stories and social media posts about 6 health topics: mammography screening, prostate-specific antigen (PSA) testing, Vitamin D supplementation, carbohydrate consumption, alcohol consumption, and breastfeeding. Participants in the no conflict (comparator) group will have no conflicting information included in these news and social media posts.

No exposure to conflict

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • + U.S. adults
  • Members of NORC's AmeriSpeak Panel (https://amerispeak.norc.org/Pages/default.aspx)
  • Able to complete web-based survey
  • Able to read in English

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NORC at the University of Chicago (online only)

Chicago, Illinois, 60603, United States

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 16, 2020

First Posted

January 30, 2020

Study Start

July 20, 2020

Primary Completion

August 31, 2020

Study Completion

August 31, 2020

Last Updated

November 10, 2020

Record last verified: 2020-11

Locations