NCT07122362

Brief Summary

This randomized controlled trial aims to evaluate the effect of an elastic lower extremity orthosis on gait and balance in children with spastic cerebral palsy who present with an in-toeing gait pattern. The study compares conventional neurodevelopmental therapy alone to therapy combined with the orthosis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 30, 2025

Completed
15 days until next milestone

First Posted

Study publicly available on registry

August 14, 2025

Completed
11 days until next milestone

Study Start

First participant enrolled

August 25, 2025

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 20, 2025

Completed
12 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2025

Completed
Last Updated

January 6, 2026

Status Verified

August 1, 2025

Enrollment Period

2 months

First QC Date

July 30, 2025

Last Update Submit

January 2, 2026

Conditions

Keywords

cerebral palsyin-toeing gaitbalanceorthosesneoprene

Outcome Measures

Primary Outcomes (1)

  • Gait parameters assessed by Edinburgh Visual Gait Analysis

    The Edinburgh Visual Gait Analysis Scale will be used to assess changes in gait patterns before and after the intervention. This scale consists of 17 items. Each item is scored between 0 and 2. A total score closer to zero indicates improved gait. The Edinburgh Visual Gait Analysis Scale was developed to quantitatively analyze gait parameters at different stages in recorded videos. During the assessment, children will be videotaped walking on a flat surface with their lower extremities bare. These recordings will assess each lower extremity during the stance and swing phases of gait.

    Baseline and 8 weeks after intervention

Secondary Outcomes (1)

  • Balance parameters assessed by Pediatric Balance Scale

    Baseline and 8 weeks after intervention

Study Arms (2)

Control Group: Neurodevelopmental Therapy

ACTIVE COMPARATOR

Participants receive conventional neurodevelopmental therapy only.

Behavioral: Neurodevelopmental Therapy

Intervention Group: Therapy + Elastic Orthosis

EXPERIMENTAL

Participants receive conventional neurodevelopmental therapy plus elastic lower extremity orthosis.

Device: Elastic Lower Extremity OrthosisBehavioral: Neurodevelopmental Therapy

Interventions

Participants in the intervention group receive conventional neurodevelopmental therapy combined with an elastic lower extremity orthosis designed to correct internal rotation deformities and improve gait and balance in children with spastic cerebral palsy. The orthosis applies elastic tension around the femoral region and tibia to target rotational problems.

Intervention Group: Therapy + Elastic Orthosis

Participants receive conventional neurodevelopmental therapy only.

Control Group: Neurodevelopmental TherapyIntervention Group: Therapy + Elastic Orthosis

Eligibility Criteria

Age18 Months - 84 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Voluntary participation
  • Diagnosis of spastic cerebral palsy
  • Gross Motor Function Classification System (GMFCS) level 1, 2, or 3
  • Age between 18 and 84 months
  • Presence of in-toeing gait pattern

You may not qualify if:

  • GMFCS level 4 or 5
  • Botulinum toxin injection or surgical intervention targeting the lower extremities or pelvis within the last 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Turkey

Ankara, Ankara, 06000, Turkey (Türkiye)

Location

Niğde Ömer Halisdemir University Bor Physical Therapy and Rehabilitation Training and Research Hospital

Niğde, Niğde Province, 51000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • BÜLENT ELBASAN, Prof.

    Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Türkiye

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 30, 2025

First Posted

August 14, 2025

Study Start

August 25, 2025

Primary Completion

October 20, 2025

Study Completion

November 1, 2025

Last Updated

January 6, 2026

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will share

De-identified individual participant data (IPD) will be made available upon reasonable request from qualified researchers with ethics approval, starting 6 months after study completion. Data sharing will be conducted under a data sharing agreement to ensure participant confidentiality.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
Individual participant data and supporting documents will be available starting 6 months after study completion and will remain available for at least 5 years.
Access Criteria
Qualified researchers with appropriate ethics committee approval may request access to the de-identified IPD and supporting documents. Data will be shared following a data sharing agreement that ensures confidentiality and appropriate use. Access requests can be made by contacting the corresponding

Locations