Human Papilloma Virus In Male Infertility

NCT07121530 | Completed DMC

• 1 other identifier: SVU-MED-DVA021-1-23-8-706
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Infertility is a major health problem worldwide and is estimated to affect 8-12% of couples in the reproductive age group. Infertility affects both men and women. Male causes for infertility are found in 50% of these couples. HPV may infect the semen ,allowing it to affect male fertility in a variety of ways.

Conditions

Male Infertility

Outcome Measures

Primary Outcomes (1)

• Investigation of Human Papilloma Virus infection in infertile males

  Investigation of Human Papilloma Virus (HPV) infection in infertile males as : all participants in the study made semen analysis and the semen were collected by masturbation after 5-7 days of abstinence. Semen parameters (semen volume, sperm concentration, progressive motility (PR) and rate of normal sperm morphology) were analyzed in a thermostat console after semen liquefaction. then Seminal Detection of HPV antibodies in infertile male by HPV ELISA Kit and also to see its effects on semen parameters in Qena government.

  2 Days

Study Arms (2)

Infertile Males Group

About 30 infertile males with genital wart

Procedure: HPV infection in infertile males

Control Group

About 20 healthy males

Procedure: HPV infection in infertile males

Interventions

HPV infection in infertile males PROCEDURE

To investigate the status of HPV infection in infertile males in Qena government, and to Analyse the effects of HPV infection on semen parameters.

Also known as: infertile males

Control Group; Infertile Males Group

Eligibility Criteria

• Age: 23 Years - 53 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study will be conducted (30)infertile males with genital wart ,control (20) attending the Dermatology, Venereology\& Andrology clinic in Qena University Hospital.

You may qualify if:

• Patients with at least 1 year of unprotected sexual intercourse without conception.
• Patients with genital warts

You may not qualify if:

• Hypergonadotropic/hypogonadotropic hypogonadism
• Azoospermia
• chromosome abnormalities
• undescended testis
• mumps orchitis

Sponsors & Collaborators

• South Valley University: lead

Study Sites (1)

Qina University hospital, South Valley University Hospital

Qina, Egypt

Location

MeSH Terms

Conditions

Infertility, Male

Condition Hierarchy (Ancestors)

Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Infertility; Male Urogenital Diseases

Study Officials

• Eisa Mohammed Hegazy, Professor

  Dermatology, Venereology and Andrology. Faculty of Medicine,South ValleyUniversity

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident at Dermatology , venereology and andrology, Faculty of medicine

Study Record Dates

• First Submitted: July 30, 2025
• First Posted: August 13, 2025
• Study Start: August 1, 2023
• Primary Completion: August 1, 2024
• Study Completion: August 10, 2024
• Last Updated: August 13, 2025

Record last verified: 2023-08

Locations

EG (1)