NCT07118904

Brief Summary

This study examines the effects of rapid dehydration-induced weight loss on combat athletes' sleep quality, cognitive skills, and isokinetic strength performance. The research documents both benefits and risks of weight-cutting practices for athletes, coaches, and medical staff in weight-class sports. Findings will guide safer weight management approaches and inform potential revisions to international weigh-in protocols, while contributing valuable insights to sports science.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
4mo left

Started Aug 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress70%
Aug 2025Aug 2026

First Submitted

Initial submission to the registry

July 29, 2025

Completed
14 days until next milestone

First Posted

Study publicly available on registry

August 12, 2025

Completed
6 days until next milestone

Study Start

First participant enrolled

August 18, 2025

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 28, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2026

Last Updated

March 16, 2026

Status Verified

March 1, 2026

Enrollment Period

9 months

First QC Date

July 29, 2025

Last Update Submit

March 12, 2026

Conditions

Keywords

Athletic PerformanceCognitive SkillsSleep QualityIsokinetic strengthEMG ResponseAnticipation Time

Outcome Measures

Primary Outcomes (6)

  • Sleep monitoring and Evaluation

    Participants' sleep assessments will be conducted with a sleep monitor, which uses impulse radio ultra-wide band (IR-UWB) radar and Doppler technology, and has been shown to provide measurements as accurate and reliable as the polysomnography device, which is considered the gold standard in sleep assessment. Total sleep and wake times and durations of the sleep phases will be obtained in minutes from the recordings of the device.

    First trial monitoring, following one week Second trial monitoring and following one week Third trial monitoring (Due to randomized counterbalanced crossover design, monitoring will be performed three times, two as experimental and one as control).

  • Isokinetic Leg Strength Measurement

    Isokinetic leg strength measurements will be made with the Cybex Norm device. Peak torque data obtained during the measurements will be recorded and used in data processing.

    First trial testing, following one week Second trial testing and following one week Third trial testing (Due to randomized counterbalanced crossover design, testing will be performed three times, two as experimental and one as control).

  • EMG Measurements

    Electrical potentials of muscle cells are recorded with electromyography (EMG) and the activities of skeletal muscles are evaluated based on changes in these potentials. EMG measurement provides information about the muscles and motor nerves involved by analyzing motor unit action potentials.

    First trial testing, following one week Second trial testing and following one week Third trial testing (Due to randomized counterbalanced crossover design, testing will be performed three times, two as experimental and one as control).

  • Stroop test

    The Stroop test is a test that reflects frontal lobe region activity.

    First trial testing, following one week Second trial testing and following one week Third trial testing (Due to randomized counterbalanced crossover design, testing will be performed three times, two as experimental and one as control).

  • Symbol Digit Modalities Test

    The Symbol Digit Modalities Test is a test that evaluates complex visual spatial scanning, sustained attention and concentration, information processing speed and working memory.

    First trial testing, following one week Second trial testing and following one week Third trial testing (Due to randomized counterbalanced crossover design, testing will be performed three times, two as experimental and one as control).

  • Montreal Cognitive Assessment

    The Montreal Cognitive Assessment test evaluates cognitive functions such as attention and concentration, executive functions, memory, language, visual construction skills, calculation and orientation. The test scores range from 0 to 30, with a cut-off score of 21. Scores of 21 and above are considered normal.

    First trial testing, following one week Second trial testing and following one week Third trial testing (Due to randomized counterbalanced crossover design, testing will be performed three times, two as experimental and one as control).

Study Arms (3)

Dehydration + Dehydrated Night Trial

EXPERIMENTAL

In this trial 3% weight loss will be achieved with sauna application by taking the body weights recorded in the pre-test as a reference. Following the dehydration application, all measurements taken in the pre-test before the application will be repeated in order after approximately 45 minutes. Athletes will be permitted to engage in a routine night without rehydration. During this period, their sleep quality will be recorded with a sleep tracker. The next day in the morning, all measurements taken in the pre-test will be repeated in order to evaluate the effect of dehydration and the possible negative effect of dehydration on sleep quality on the dependent variables. Following the completion of the morning measurements, the athletes will be permitted to consume fluids and food within two hours in order to reach their body weights in the pre-test. All tests will be reapplied for the last time to the athletes who have reached the state of rehydration, respectively.

Other: Rapid weight loss through dehydration

Dehydration + Rehydrated Night Trial

EXPERIMENTAL

In this trial 3% weight loss will be achieved with sauna application by taking the body weights recorded in the pre-test as a reference. Following the dehydration application, all measurements taken in the pre-test before the application will be repeated in order after approximately 45 minutes, with the athlete refraining from consuming any food or liquid. Athletes will be permitted to rehydrate after the second measurements and will be asked to spend a routine night. The remaining tests will be repeated in accordance with the experimental trial 1 protocol.

Other: Rapid weight loss through dehydration

Control Trial

NO INTERVENTION

No intervention will be conducted. All tests to be used to measure dependent variables will be conducted in accordance with the Experimental trial 1 protocol.

Interventions

Dehydration will be induced by exposing athletes to sauna heat with an average temperature of 70-80°C. The participants will undergo consecutive 15 minute sessions in sauna with 5 minute breaks until 3% weight loss is achieved. No liquids or food will be consumed between sessions.

Dehydration + Dehydrated Night TrialDehydration + Rehydrated Night Trial

Eligibility Criteria

Age17 Years - 28 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsMale individuals will be included due to the fact that women's hormonal responses may cause heterogeneous findings and the difficulty in interpreting the findings due to their hormonal profile.
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Voluntary participation
  • Being combat athletes with prior rapid weight loss experience
  • No existing health conditions
  • No orthopedic injuries

You may not qualify if:

  • Using of sleep-related medications
  • Complications During the Intervention: Participants who experience any complications during experimental intervention.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bolu Abant İzzet Baysal University, Faculty of Sport Sciences,

Bolu, 14030, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

DehydrationWeight LossWeight CyclingSleep Initiation and Maintenance Disorders

Condition Hierarchy (Ancestors)

Water-Electrolyte ImbalanceMetabolic DiseasesNutritional and Metabolic DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsBody Weight ChangesBody WeightSigns and SymptomsWeight GainSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Study Officials

  • Umid Karli, PhD

    Bolu Abant İzzet Baysal University, Faculty of Sport Sciences, Department of Coaching Education

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Kutlu Aydın, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: Randomized counterbalanced crossover design study (Two experimental trial a control trial)
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 29, 2025

First Posted

August 12, 2025

Study Start

August 18, 2025

Primary Completion (Estimated)

May 28, 2026

Study Completion (Estimated)

August 30, 2026

Last Updated

March 16, 2026

Record last verified: 2026-03

Locations