BRAZILIAN REGISTRY OF CHRONIC NON-COMMUNICABLE DISEASES IN PEOPLE LIVING WITH HIV/AIDS

NCT07118683 | Not Yet Recruiting

• 1 other identifier: CAAE: 81912924.9.1001.0070
• Study Type: observational
• Target: 2,100
• Locations: 0 countries
• Sites: N/A

Brief Summary

BRAVO proposes the establishment of a comprehensive registry of chronic noncommunicable diseases (NCDs), providing crucial data for the formulation of effective health policies for people living with HIV/AIDS (PLWHA). The study will comprise a cross-sectional and longitudinal assessment: the cross-sectional study, will collect on the study allocation sociodemographic data, risk factors related to the main NCDs, physical examination data and samples for determination of biochemical and metabolic parameters; the longitudinal study, lasting 1 year and with the possibility of extension, will follow the participants to identify new diagnoses in the broad spectrum of NCDs. To this end, the study will include co-participating research centers from the 5 Brazilian geographic macro-regions.

Conditions

AIDS (Acquired Immunodeficiency Syndrome); Cardiovascular and Cerebrovascular Diseases; Respiratory Comorbidities; Chronic Kidney Disease; Cancer

Keywords

Acquired Immunodeficiency Syndrome; Cardiovascular Diseases; Respiratory Tract Diseases; Renal Insufficiency, Chronic; Neoplasms; Treatment Adherence and Compliance; Quality of Life; Prevalence; Incidence; Brazil; Cross-sectional study; Prospective cohort

Outcome Measures

Primary Outcomes (2)

• Prevelance of chronic non-communicable diseases and mental disorders

  Prevalence of cardiovascular diseases, non-infectious respiratory diseases, chronic kidney disease and cancers, depression, dependence on alcohol and illicit substances, self-harm and physical violence.

  Baseline

• Incidence of chronic non-communicable diseases and mental disorders

  Cardiovascular diseases, non-infectious respiratory diseases, chronic kidney disease and cancers, and depression.

  1 year

Secondary Outcomes (3)

• Prevalence of metabolic and behavioral risk factors for chronic non-communicable diseases

  Baseline

• Prevalence of participants with good adherence to antiretroviral therapy.

  Baseline and 1 year after

• Profile of Quality of life of participants

  Baseline and 1 year after

Other Outcomes (1)

• Incidence of adverse events potentially associated with antiretroviral therapy

  Baseline and 1 year after

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

People living with HIV or Aids.

You may qualify if:

• Adults aged 18 or over;
• Any gender identity;
• Confirmed HIV or AIDS diagnosis;
• Signature of consent form

You may not qualify if:

• Indigenous population or those in prison in open or closed regimes;
• Patients hospitalized at the time of signing the Consent Form.

Sponsors & Collaborators

• Hospital Alemão Oswaldo Cruz: lead
• Ministry of Health, Brazil: collaborator

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome; Cerebrovascular Disorders; Renal Insufficiency, Chronic; Neoplasms; Cardiovascular Diseases; Respiratory Tract Diseases; Treatment Adherence and Compliance

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Health Behavior; Behavior

Study Officials

• Victor Sato

  Hospital Alemão Oswaldo Cruz

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Victor Sato

CONTACT

+551135490515; victorhsato@gmail.com

Rosa Lucchetta

CONTACT

+551135490515; rosa.lucchetta@haoc.com.br

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 12 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 6, 2025
• First Posted: August 12, 2025
• Study Start: August 15, 2025
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: August 12, 2025

Record last verified: 2025-08