Effects of Ultrasound and Infrared on Joint Pain and Movement in Hemophilia A Patients.

NCT07116993 | Completed DMC

• 1 other identifier: kuhs/dpt/umt-skt-017
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to compare the effectiveness of therapeutic ultrasound and infrared in managing hemarthrosis in patients with Hemophilia A, focusing on specific outcomes like joint pain, swelling, muscle atrophy, and range of motion.The main question to it is either one from both of the modalities are effective for hemophilia patients or not? comparison will be done to check the effectiveness of ultrasound and infrared on patients of both groups. participants will:

1. 1.get the treatment according to their respective groups
2. 2.Both groups were given 4 sessions for 4 weeks.

Conditions

Hemophilia A

Keywords

hemophilia A; ultrasound; infrared; joint health

Outcome Measures

Primary Outcomes (3)

• joint pain

  Joint Pain: Measured using the Numerical Pain Rating Scale (NPRS) to quantify changes in pain severity. 0 indicates no pain while 10 indicates severe pain

  3 weeks

• ROM

  Range of Motion (ROM): Measured using a goniometer to assess improvements in flexion and extension angles, measured in degrees, in the joint.

  3 weeks

• Swelling

  Assessed based on circumference measurements around knee, elbow and ankle joint using inelastic tape measure in centimeters around the affected joint to detect reductions in swelling.

  3 weeks

Study Arms (2)

ultrasound

EXPERIMENTAL

ultrasound group containing 15 participants who were given ultrasound therapy for 10 minutes along with the conventional physiotherapy.

Device: theraputic ultrasound

infrared radiation

EXPERIMENTAL

infrared radiation group containing 15 participants who were treated with infrared therapy for 10 minutes along with the conventional physiotherapy.

Device: infrared radiation

Interventions

theraputic ultrasound DEVICE

Ultrasound is a mechanical sound wave with frequencies above human hearing, requiring a medium like air or tissue to travel, commonly used in imaging.

ultrasound

infrared radiation DEVICE

Infrared, in contrast, is electromagnetic radiation associated with heat, doesn't need a medium, and is used in applications like thermal imaging and remote controls.

infrared radiation

Eligibility Criteria

• Gender Eligibility Details: males with hemophilia A
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with hemophilia A (Eid \& Aly, 2015) .
• Who had the Bleeding frequency of atleast once per week (Eid \& Aly, 2015).
• Males with hemophilia A
• Irrespective of their therapeutic regime administered by their hematologists (Donoso-Úbeda, Meroño-Gallut, López-Pina, \& Cuesta Barriuso, 2020) .

You may not qualify if:

• Patients who had surgical procedures (Eid \& Aly, 2015) .
• Patients who were suffering from co-morbidities along with Hemophilia A.
• Patients who had any other disability/deformity.
• Who were receiving other physiotherapy treatment (Donoso-Úbeda et al., 2020) .
• Who failed to sign the informed consent (Donoso-Úbeda et al., 2020)

Sponsors & Collaborators

• Danyal Ahmad: lead

Study Sites (1)

Danyal Ahmad

Sialkot, Punjab Province, 51010, Pakistan

Location

MeSH Terms

Conditions

Hemophilia A

Condition Hierarchy (Ancestors)

Blood Coagulation Disorders, Inherited; Blood Coagulation Disorders; Hematologic Diseases; Hemic and Lymphatic Diseases; Coagulation Protein Disorders; Hemorrhagic Disorders; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: head supervior

Study Record Dates

• First Submitted: October 30, 2024
• First Posted: August 12, 2025
• Study Start: March 1, 2024
• Primary Completion: March 30, 2024
• Study Completion: June 15, 2024
• Last Updated: August 12, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)