Key Insights

Highlights

Success Rate

87% trial completion (above average)

Published Results

96 trials with published results (26%)

Research Maturity

217 completed trials (59% of total)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

8.8%

32 terminated out of 365 trials

Success Rate

87.1%

+0.6% vs benchmark

Late-Stage Pipeline

32%

117 trials in Phase 3/4

Results Transparency

44%

96 of 217 completed with results

Key Signals

96 with results87% success32 terminated

Data Visualizations

Phase Distribution

221Total
Not Applicable (36)
Early P 1 (3)
P 1 (44)
P 2 (21)
P 3 (73)
P 4 (44)

Trial Status

Completed217
Recruiting40
Unknown40
Terminated32
Active Not Recruiting14
Not Yet Recruiting9

Trial Success Rate

87.1%

Benchmark: 86.5%

Based on 217 completed trials

Clinical Trials (365)

Showing 20 of 20 trials
NCT05568719Phase 3RecruitingPrimary

Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively

NCT06809972Recruiting

Synovial Proliferation on Routine Ultrasound: Active or Inactive?

NCT05987449Phase 1RecruitingPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

NCT04563520Phase 3RecruitingPrimary

SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis

NCT07226206Phase 1RecruitingPrimary

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

NCT03217032Phase 1RecruitingPrimary

Lentiviral FVIII Gene Therapy

NCT06147414Recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

NCT06820515Recruiting

ATHNdataset Registry

NCT07539402Not Yet RecruitingPrimary

Searching Patterns In the Robustness of Immunological FVIII Tolerance

NCT03588299Phase 1Active Not RecruitingPrimary

Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle"

NCT06222697RecruitingPrimary

A Study to Learn More About the Safety of Damoctocog-alfa-pegol When Used in Routine Medical Care in Korean Participants With Hemophilia A

NCT07088458Not Yet RecruitingPrimary

An Observational Study to Learn More About How Well Damoctocog Alfa Pegol Works in Previously Treated Children With Hemophilia A

NCT05145127Phase 3RecruitingPrimary

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

NCT07416526Phase 3RecruitingPrimary

A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A

NCT05643560Active Not RecruitingPrimary

An Observational Study Called JOIHA to Learn More About How Well the Treatment With Jivi Works to Prevent Problems With Joints in Adults With Hemophilia A.

NCT07523399RecruitingPrimary

Joint Health, Balance and Quality of Life in Adults With Hemophilia A

NCT03932201Active Not RecruitingPrimary

Evaluating Effectiveness and Long Term Safety of Damoctocog Alfa Pegol in Patients, Who Have Been Diagnosed With Hemophilia A

NCT04461639Active Not RecruitingPrimary

Study to Learn More About the Safety of Drug Jivi Over a Long Period of Time in Previously Treated Patients With Hemophilia A (Bleeding Disorder Resulting From a Lack of FVIII) Who Are Receiving Jivi Regularly at Their Treating Doctors to Prevent Bleeding

NCT05932914Not Yet RecruitingPrimary

Liver Biopsy Following Gene Therapy For Hemophilia

NCT03315455Phase 3CompletedPrimary

Efficacy, Safety, and Pharmacokinetic Study of Prophylactic Emicizumab Versus No Prophylaxis in Hemophilia A Participants

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