Prediction of SBP in Cirrhotic Patients by Platlet Count, Na and AlBl Index.

NCT07116369 | Not Yet Recruiting

• 1 other identifier: Soh-Med--25-7-10MS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate whether integrating serum sodium levels and platelet count with the Albumin-Bilirubin (ALBI) score can improve the early prediction of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with ascites. SBP is a common and potentially life-threatening complication of cirrhosis. Identifying at-risk patients early using simple, routine laboratory parameters could enhance risk stratification, guide monitoring strategies, and reduce associated morbidity and mortality. Participants will be Adult patients (≥18 years) with liver cirrhosis and ascites undergoing diagnostic paracentesis at Sohag University Hospital.

Conditions

Spontaneous Bacterial Peritonitis

Keywords

Spontaneous bacterial peritonitis; SBP; Liver cirrhosis; ABLI score; Ascites

Outcome Measures

Primary Outcomes (1)

• Occurrence of SBP, ALBI score, s.sodium, platelet count

  Outcome of SBP in cirrhotic patients by measurement of ALBI score, platelet count and s.sodium

  Within 1 week

Study Arms (1)

Ascites patients

\>18 yr old Patients with liver cirrhosis and ascites, peritoneal aspirate, ALBI score, plaltlet, serum sodium will be recorded

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

adult patients (≥18 years) with liver cirrhosis and ascites who underwent diagnostic paracentesis in sohag university hospitals

You may qualify if:

• adult patients (≥18 years) with liver cirrhosis and ascites who underwent diagnostic paracentesis.

You may not qualify if:

• obstructive jaundice
• Recent antibiotic use \< 7 days
• Secondary pertonitis (bowel perforation)
• Advanced Hepatocelluar carcinoma
• End-stage renal disease requiring dialysis
• Use of immunosuppressive therapy
• Incomplete laboratory or clinical data.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag university hospitals

Sohag, Egypt

Location

MeSH Terms

Conditions

Liver Cirrhosis; Ascites

Condition Hierarchy (Ancestors)

Liver Diseases; Digestive System Diseases; Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Shimaa H Mahmoud, MBBS

CONTACT

+201120237891; shaimaa_helmy_post@med.sohag.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Internal Medicine Resident Doctor

Study Record Dates

• First Submitted: July 25, 2025
• First Posted: August 11, 2025
• Study Start: August 1, 2025
• Primary Completion: September 1, 2025
• Study Completion: December 1, 2025
• Last Updated: August 11, 2025

Record last verified: 2025-07

Locations

EG (1)