ARS vs ARS With Arthrocentesis and PRP Injection in DDWR

NCT07115797 | Not Yet Recruiting

• 1 other identifier: ARS+- PRP & Arthrocentesis
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study will be conducted to assess the effect of anterior repositioning splint and arthrocentesis with platelet-rich plasma injection compared to anterior repositioning splint only, in TMD patients with anterior disc displacement with reduction

Conditions

TMJ Disc Displacement With Reduction; TMD; PRP Injection

Keywords

ARS-PRP-Arthrocentsis

Outcome Measures

Primary Outcomes (1)

• Maximum pain-free interincisal opening measured in mm by caliper

  from enrollment to the end of study at 6 months

Secondary Outcomes (1)

• Pain measured by VAS scale

  from enrollment to the end of study at 6 months

Study Arms (2)

Comparator

ACTIVE COMPARATOR

ARS

Other: ARS

intervention

ACTIVE COMPARATOR

arthrocentesis then PRP injection and then ARS

Other: arthrocentesis - PRP injection -ARS

Interventions

arthrocentesis - PRP injection -ARS OTHER

oarthrocentesis then PRP injection and then ARS

intervention

ARS OTHER

Insertion Of ARS Only

Comparator

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients suffering from internal derangement anterior disc displacement
• Mouth Opening: Limited range of motion or difficulty with full mouth opening
• Symptoms: Patients who report typical symptoms of TMJ dysfunction, such as pain, discomfort, or clicking sounds in the joint, especially when opening or closing the mouth.
• Clicking: Audible clicking.
• Pain: Pain or tenderness around the TMJ, often radiating to the ear, temple, or neck.

You may not qualify if:

• Blood dyscrasias and Uncontrolled systemic diseases.
• Rheumatoid Arthritis.
• Infection in the pre-auricular area.

Sponsors & Collaborators

• Cairo University: lead

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: the observers will be blind to which group this case belongs. evaluators, and statisticians will be blinded.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Master's candidate

Study Record Dates

• First Submitted: August 4, 2025
• First Posted: August 11, 2025
• Study Start: September 1, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: August 11, 2025

Record last verified: 2025-08