NCT07114952

Brief Summary

This study is a randomized controlled experimental trial designed to examine the effect of alternative nasal breathing exercises on blood pressure and perceived stress levels in patients with hypertension. The study sample includes a total of 52 patients, with 26 in the intervention group and 26 in the control group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 6, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 26, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 26, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

July 29, 2025

Completed
13 days until next milestone

First Posted

Study publicly available on registry

August 11, 2025

Completed
Last Updated

August 11, 2025

Status Verified

August 1, 2025

Enrollment Period

5 months

First QC Date

July 29, 2025

Last Update Submit

August 4, 2025

Conditions

Keywords

HypertensionBreathing ExercisesBlood pressureStressNursing

Outcome Measures

Primary Outcomes (1)

  • Change in systolic and diastolic blood pressure

    The blood pressure of the patients in the control group was measured twice, at the beginning of the study and 1 month later. In the measurement to be performed in the morning hours, the patients rested for 5 minutes in a calm environment before the measurement and then the measurement was made from the brachial artery in the arm. The same automatic sphygmomanometer was used for blood pressure measurement in all patients. " https://www.stridebp.org/bp-monitors/ " A blood pressure measuring device listed at

    Baseline and 4 weeks after intervention

Secondary Outcomes (2)

  • Change in perceived stress scores

    Baseline and 4 weeks after intervention

  • Change in self-measured home blood pressure

    Daily measurements during the 4-week intervention period

Study Arms (2)

alternative nasal breathing exercise intervention group

EXPERIMENTAL

The intervention group of 26 participants practiced an alternative nasal breathing exercise. This group practiced alternate nasal breathing exercise for 4 weeks.

Behavioral: alternative nasal breathing

control group

NO INTERVENTION

The group consisted of 26 participants. No intervention was administered. Participants continued their usual care without any additional exercises or treatments during the study period.

Interventions

The alternate nasal breathing exercise involves breathing in and out through both nostrils in a certain pattern and for a certain period of time. For example, an individual who breathes in through the right nostril for 5 seconds with the left nostril closed, then closes the right nostril and exhales through the left nostril for 5 seconds. Then he/she inhales through the left nostril for 5 seconds and exhales through the right nostril. A total of 6 breaths are taken per minute. The application is applied for 5 minutes, the patient rests in a calm environment for two minutes and the application is performed for another 5 minutes. In order to increase the compliance of individuals with the application, a sample video was watched and application instructions were given by the researcher. The application was performed while the patients were in an upright sitting position.

alternative nasal breathing exercise intervention group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged between 18 and 65,
  • Literate,
  • Diagnosed with hypertension at least 6 months ago,
  • No change in hypertension medications in the last three months,
  • Functionally capable of performing alternative nasal breathing exercises,
  • Patients who volunteered to participate in the study were included.

You may not qualify if:

  • Patients with psychiatric diagnoses,
  • Patients with cognitive impairment,
  • Patients practicing yoga or breathing exercises for hypertension,
  • Patients with heart failure, cancer, kidney failure, or respiratory diseases were not included in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Adana City Training and Research Hospital, Cardiology Outpatient Clinic

Adana, Yüreğir, 1370, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: "In this randomized controlled trial, participants were divided into two groups: an intervention group performing alternate nasal breathing exercises and a control group with no intervention. Outcomes were measured before and 4 weeks after the intervention period."
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research assistant

Study Record Dates

First Submitted

July 29, 2025

First Posted

August 11, 2025

Study Start

January 6, 2025

Primary Completion

May 26, 2025

Study Completion

May 26, 2025

Last Updated

August 11, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share

Locations