Brief Summary

Dementia is observed in 80% of people living with advanced stage Parkinson's disease, however, there are inadequate opportunities for early and effective diagnosis of dementia in current clinical practice. This study aims to identify whether a new tool called PDCogniCare, can improve detection of dementia in people living with Parkinson's disease, and to explore what factors might influence its use in healthcare services.

Trial Health

Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

275

participants targeted

Target at P75+ for not_applicable

Timeline

8mo left

Started Aug 2025

Status

not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

1.4 years study duration

Study Progress53%

Aug 2025Dec 2026

First Submitted

Initial submission to the registry

August 3, 2025

Completed

8 days until next milestone

First Posted

Study publicly available on registry

August 11, 2025

Completed

7 days until next milestone

Study Start

First participant enrolled

August 18, 2025

Completed

1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

August 11, 2025

Status Verified

July 1, 2025

Enrollment Period

1.4 years

First QC Date

August 3, 2025

Last Update Submit

August 3, 2025

Conditions

Dementia (Diagnosis)Parkinson Disease Dementia (PDD)Parkinson Disease (PD)

Keywords

Parkinson&amp;#39;s diseaseDementiaCognitive evaluationImplementation

Outcome Measures

Primary Outcomes (1)

Change in percentage of people with Parkinson's disease diagnosed with dementia
12 months from enrolment

Secondary Outcomes (1)

Change in percentage of people with Parkinson's disease diagnosed with mild cognitive impairment
12 months from enrolment

Study Arms (1)

PDCogniCare

OTHER

All eligible people living with Parkinson's disease who consent to participate will be registered into the PDCogniCare platform.

Other: PDCogniCare platform

Interventions

PDCogniCare platformOTHER

Digital platform designed to support early and accurate detection of dementia in people living with Parkinson's disease

PDCogniCare

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

People living with idiopathic Parkinson's disease, one year or more post-diagnosis, attending Movement Disorder Clinics

You may not qualify if:

People with severe Parkinson's disease who aren't able to communicate
People with comorbid neurological conditions (e.g. Stroke)

Contact the study team to confirm eligibility.

Related Publications (2)

Pourzinal D, King J, Sivakumaran K, Yang J, McCann E, Mitchell LK, Brooks D, Lehn A, Liddle J, Pachana NA, Tinson H, Shrubsole K, Bailey DX, Dissanayaka NN. Evaluating evidence for a neuropsychological toolkit to predict cognitive decline in PD: A systematic review. Clin Neuropsychol. 2025 Jun 4:1-28. doi: 10.1080/13854046.2025.2511966. Online ahead of print.
PMID: 40464273BACKGROUND
Pourzinal D, Elgey C, Bailey DX, Yang J, Lehn A, Tinson H, Liddle J, Brooks D, Naismith SL, Shrubsole K, Marsh R, Mitchell LK, Pachana NA, King J, Dissanayaka NN. Diagnosis, evaluation & management of cognitive disorders in Parkinson's disease: A systematic review. Int Psychogeriatr. 2025 May 12:100081. doi: 10.1016/j.inpsyc.2025.100081. Online ahead of print.
PMID: 40360335BACKGROUND

MeSH Terms

Conditions

DementiaDiseaseParkinson Disease

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental DisordersPathologic ProcessesPathological Conditions, Signs and SymptomsParkinsonian DisordersBasal Ganglia DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Central Study Contacts

Nadeeka Dissanayaka

CONTACT

+617 3346 5577 pdcognicare@uq.edu.au

Tiffany Au

CONTACT

dnmh@uq.edu.au

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: HEALTH SERVICES RESEARCH
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

August 3, 2025

First Posted

August 11, 2025

Study Start

August 18, 2025

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

August 11, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing: Will not share

Enhancing Utility of Neuropsychological Evaluation for Earlier and Effective Diagnosis of Dementia in Parkinson's Disease

Brief Summary

Trial Health

Trial Health Score

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

PDCogniCare

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Related Publications (2)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

Data Sharing

Brief Summary

Trial Health

Trial Health Score

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

PDCogniCare

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Related Publications (2)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

Data Sharing