Effect of Lyophilized Cornelian Cherry on Anaerobic Performance in Young Football Players

NCT07114341 | Completed

• 1 other identifier: CORNELIANCHERRYFOOTBALLSTUDY
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if a lyophilized Cornelian Cherry supplement works to improve anaerobic performance and reduce fatigue in young football players (U14-U19 age group). The main questions it aims to answer are:

• Does taking a lyophilized Cornelian Cherry supplement improve participants' anaerobic performance as measured by the Running-based Anaerobic Sprint Test (RAST)?
• Does the supplement reduce participants' levels of fatigue after strenuous exercise? Researchers will measure participants' performance and fatigue levels before the study begins and compare them to the levels measured after 1 week of taking the cranberry supplement. This will help determine the effect of the supplement. Participants will:
• Take 30 grams of lyophilized Cornelian Cherry powder every day for 1 week.
• Visit the study center at the beginning and at the end of the 1-week period for checkups and tests.
• Undergo anthropometric measurements (such as height, weight, and body composition) at the start of the study.
• Perform a Running-based Anaerobic Sprint Test (RAST) and a fatigue test at the start and end of the study.

Conditions

Sport Nutrition; Sports Performance in Children; Ergogenic Athletic Performance; Ergogenic Support; Sports Nutritional Sciences

Keywords

cranberry; sports nutrition; ergogenic acids; football; adolecent athletes

Outcome Measures

Primary Outcomes (1)

• Running-Based Anaerobic Sprint Test (RAST) - Performance Test

  The RAST is a test consisting of six 35-meter sprints at maximum speed, with a 10-second rest interval between each sprint. In this test, power is calculated for each sprint using body mass and the resulting performance data (Power = (Total body mass x Distance2) / Time3). The highest recorded number is called maximum power; the lowest number is called minimum power; and the sum of the six sprints divided by six is called average power. Muscle fatigue is assessed using the Fatigue Index (Maximum Power - Minimum Power) / Sum of the 6 sprint times). A lower value indicates that athletes have better muscular ability to maintain their performance without fatigue.

  From enrollment to the end of study at 1 week

Secondary Outcomes (12)

• Anthropometric Measurements - Body weight (kg)

  From enrollment to the end of study at 1 week

• Anthropometric Measurements - Height

  1 week

• Body Mass Index

  From enrollment to the end of study at 1 week

• Anthropometric Measurements - Fat Mass

  From enrollment to the end of study at 1 week

• Anthropometric Measurements - Fat ratio calculation

  From enrollment to the end of study at 1 week

Study Arms (2)

Baseline

NO INTERVENTION

In order to determine the standard performance of the adolescent football players in the first stage before the intervention, a Running-Based Anaerobic Sprint Test (RAST) was applied to the adolescent football players on a grass field in an open-air environment after a 10-minute warm-up exercise.

Cranberry Intervention

ACTIVE COMPARATOR

In the second phase of the study, adolescent soccer players were given 30 grams of freeze-dried cranberries containing 1187 mg/100 g anthocyanins daily for 1 week. To determine post-intervention performance, the adolescent soccer players underwent a 10-minute warm-up exercise followed by a Running-Based Anaerobic Sprint Test (RAST) on a grass field in an outdoor environment.

Other: Cranberry Intervention

Interventions

Cranberry Intervention OTHER

30 grams of lyophilized cranberry containing 1187 mg/100 g anthocyanins were given for 7 days.

Cranberry Intervention

Eligibility Criteria

• Age: 14 Years - 19 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• ages of adolescent football

You may not qualify if:

• Disease diagnosis or history,
• Regular medication use,
• Regular nutritional supplement use,
• Being under 14 years of age,
• Being over 19 years of age.

Sponsors & Collaborators

• Istanbul Bilgi University: lead

Study Sites (1)

Istanbul Bilgi University

Istanbul, Turkey (Türkiye)

Location

Related Publications (15)

• Braakhuis AJ, Somerville VX, Hurst RD. The effect of New Zealand blackcurrant on sport performance and related biomarkers: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2020 May 27;17(1):25. doi: 10.1186/s12970-020-00354-9.

  PMID: 32460873 BACKGROUND

• Donno D, Neirotti G, Fioccardi A, Razafindrakoto ZR, Tombozara N, Mellano MG, Beccaro GL, Gamba G. Freeze-Drying for the Reduction of Fruit and Vegetable Chain Losses: A Sustainable Solution to Produce Potential Health-Promoting Food Applications. Plants (Basel). 2025 Jan 9;14(2):168. doi: 10.3390/plants14020168.

  PMID: 39861522 BACKGROUND

• Jastrzebska AD. Comparison of usefulness of two tests measuring anaerobic performance of untrained and soccer-training girls U12. Sci Rep. 2023 Nov 9;13(1):19498. doi: 10.1038/s41598-023-46825-2.

  PMID: 37945713 BACKGROUND

• Rizal M, Segalita C, Mahmudiono T. The Relationship between Body Mass Index, Body Fat Percentage, and Dietary Intake with Muscle Fatigue in Adolescent Football Players. J Nutr Sci Vitaminol (Tokyo). 2020;66(Supplement):S134-S136. doi: 10.3177/jnsv.66.S134.

  PMID: 33612582 BACKGROUND

• Bayram HM, Iliaz R, Gunes FE. Effects of Cornus mas L. on anthropometric and biochemical parameters among metabolic associated fatty liver disease patients: Randomized clinical trial. J Ethnopharmacol. 2024 Jan 10;318(Pt B):117068. doi: 10.1016/j.jep.2023.117068. Epub 2023 Aug 21.

  PMID: 37611681 BACKGROUND

• Kazimierski M, Regula J, Molska M. Cornelian cherry (Cornus mas L.) - characteristics, nutritional and pro-health properties. Acta Sci Pol Technol Aliment. 2019 Jan-Mar;18(1):5-12. doi: 10.17306/J.AFS.0628.

  PMID: 30927747 BACKGROUND

• Godwin C, Cook MD, Willems MET. Effect of New Zealand Blackcurrant Extract on Performance during the Running Based Anaerobic Sprint Test in Trained Youth and Recreationally Active Male Football Players. Sports (Basel). 2017 Sep 15;5(3):69. doi: 10.3390/sports5030069.

  PMID: 29910429 BACKGROUND

• Khoo HE, Azlan A, Tang ST, Lim SM. Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits. Food Nutr Res. 2017 Aug 13;61(1):1361779. doi: 10.1080/16546628.2017.1361779. eCollection 2017.

  PMID: 28970777 BACKGROUND

• Bowtell J, Kelly V. Fruit-Derived Polyphenol Supplementation for Athlete Recovery and Performance. Sports Med. 2019 Feb;49(Suppl 1):3-23. doi: 10.1007/s40279-018-0998-x.

  PMID: 30671906 BACKGROUND

• Bolat E, Saritas S, Duman H, Eker F, Akdasci E, Karav S, Witkowska AM. Polyphenols: Secondary Metabolites with a Biological Impression. Nutrients. 2024 Aug 3;16(15):2550. doi: 10.3390/nu16152550.

  PMID: 39125431 BACKGROUND

• Volpe-Fix AR, de Franca E, Silvestre JC, Thomatieli-Santos RV. The Use of Some Polyphenols in the Modulation of Muscle Damage and Inflammation Induced by Physical Exercise: A Review. Foods. 2023 Feb 21;12(5):916. doi: 10.3390/foods12050916.

  PMID: 36900433 BACKGROUND

• Sawada Y, Ichikawa H, Ebine N, Minamiyama Y, Alharbi AAD, Iwamoto N, Fukuoka Y. Effects of High-Intensity Anaerobic Exercise on the Scavenging Activity of Various Reactive Oxygen Species and Free Radicals in Athletes. Nutrients. 2023 Jan 1;15(1):222. doi: 10.3390/nu15010222.

  PMID: 36615878 BACKGROUND

• He F, Li J, Liu Z, Chuang CC, Yang W, Zuo L. Redox Mechanism of Reactive Oxygen Species in Exercise. Front Physiol. 2016 Nov 7;7:486. doi: 10.3389/fphys.2016.00486. eCollection 2016.

  PMID: 27872595 BACKGROUND

• Capra ME, Stanyevic B, Giudice A, Monopoli D, Decarolis NM, Esposito S, Biasucci G. Nutrition for Children and Adolescents Who Practice Sport: A Narrative Review. Nutrients. 2024 Aug 22;16(16):2803. doi: 10.3390/nu16162803.

  PMID: 39203939 BACKGROUND

• Amawi A, Khataybeh B, Al Aqaili R, Ababneh N, Alnimer L, Qoqazeh A, Oukal F, Jahrami H, Mousa Ay K, Al Saoud H, Ghazzawi H. Junior athletes' nutritional demands: a narrative review of consumption and prevalence of eating disorders. Front Nutr. 2024 Sep 24;11:1390204. doi: 10.3389/fnut.2024.1390204. eCollection 2024.

  PMID: 39381351 BACKGROUND

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Masking Details: Not suitable for masking.
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor, Head of Nutrition and Dietetic Department

Model Details: This study designed as an intervention study.

Study Record Dates

• First Submitted: August 3, 2025
• First Posted: August 11, 2025
• Study Start: April 1, 2025
• Primary Completion: April 30, 2025
• Study Completion: April 30, 2025
• Last Updated: September 8, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)