Combined Effects of Global Posture Re-education and Active Cycle of Breathing Technique in COPD

NCT06308289 | Completed DMC

• 1 other identifier: REC/RCR&AHS/23/0361
• Study Type: interventional
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

The randomized controlled trial will involve 30 participants, with Group A receiving GPRM and ACBT, while Group B follows the conventional COPD model that includes ACBT only.Assessments of heart rate, physical fitness, and quality of life will contribute to a nuanced understanding of joint function, informing future COPD treatment paradigms.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

chronic obstructive Pulmonary disease; Posture; Work of breathing

Outcome Measures

Primary Outcomes (6)

• SF- 36 Questionnaire

  The 36-Item Short Form Survey (SF-36) is an outcome measure instrument that is often used, well-researched, self-reported measure of health. It stems from a study called the Medical Outcomes Study for the objective measure of the quality of life. It comprises 36 questions that cover eight domains of health: 1. Limitations in physical activities because of health problems. 2. Limitations in social activities because of physical or emotional problems 3. Limitations in usual role activities because of physical health problems 4. Bodily pain 5. General mental health (psychological distress and well-being) 6. Limitations in usual role activities because of emotional problems 7. Vitality (energy and fatigue) 8. General health perceptions Scores for the different domains are converted and pooled using a scoring key, for a total score indicating a range of low to high QOL

  12 Weeks

• FEV1/FVC ratio

  The individual inhales maximally and then exhales forcefully into a spirometer, measuring lung volume and airflow. The procedure may be repeated multiple times to ensure accurate and consistent results.

  12 Weeks

• 6-minute walk test

  The Six-Minute Walk Test (6MWT) assesses exercise capacity. Participants are briefed and baseline vital signs are recorded. The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity.

  12 Weeks

• Photogrammetry

  Photogrammetry is a research tool used in COPD studies to assess physical changes. It involves capturing and analyzing images of patients to measure anatomical features and body movement.

  12 Weeks

• Forced expiratory volume (FEV1)

  The individual inhales maximally and then exhales forcefully into a spirometer, measuring lung volume and airflow. The procedure may be repeated multiple times to ensure accurate and consistent results.

  12 Weeks

• Forced vital capacity (FVC)

  The individual inhales maximally and then exhales forcefully into a spirometer, measuring lung volume and airflow. The procedure may be repeated multiple times to ensure accurate and consistent results.

  12 Weeks

Study Arms (2)

Group A

EXPERIMENTAL

GPRM and ACBT

Other: Global Posture Re-education; Other: Active Cycle of Breathing Technique

Group B

ACTIVE COMPARATOR

Standard Care for COPD (ACBT)

Other: Active Cycle of Breathing Technique

Interventions

Global Posture Re-education OTHER

Focusing on postural correction and movement patterns

Group A

Active Cycle of Breathing Technique OTHER

Emphasizing breathing control, thoracic expansion, and mucus clearance techniques

Group A; Group B

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 40-75 years diagnosed with stable COPD (according to GOLD guidelines).
• Patients of both genders
• FEV1: FVC ranging from 68 - 69%.
• Predicted FEV1 of less than 70%.
• Willingness to participate

You may not qualify if:

• Acute Exacerbation of COPD
• Participants with severe comorbidities, such as unstable cardiovascular diseases (e.g., recent myocardial infarction, uncontrolled hypertension)
• Participants diagnosed with respiratory conditions other than COPD (such as asthma, interstitial lung disease)
• Individuals who have undergone major thoracic or abdominal surgery within the past three months
• Individuals with severe mental health conditions (such as uncontrolled psychosis or severe depression)
• Pregnant or lactating individuals.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Social Security Hospital

Gujranwala, Punjab Province, 52200, Pakistan

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Muhammad Faizan Hamid, MS-CPPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized controlled trial

Study Record Dates

• First Submitted: March 4, 2024
• First Posted: March 13, 2024
• Study Start: March 3, 2024
• Primary Completion: June 5, 2024
• Study Completion: June 15, 2024
• Last Updated: July 23, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)