NCT07105085

Brief Summary

This retrospective cohort study investigates the long-term outcomes of ABO-incompatible (ABO-I) versus ABO-compatible (ABO-C) living donor liver transplantation (LDLT). A total of 511 patients at a single high-volume transplant center in Korea. The study aims to compare overall survival and the incidence of biliary complications.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
511

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2012

Longer than P75 for all trials

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
11 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
2.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2025

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

July 29, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

August 5, 2025

Completed
Last Updated

August 5, 2025

Status Verified

July 1, 2025

Enrollment Period

11 years

First QC Date

July 29, 2025

Last Update Submit

July 29, 2025

Conditions

Liver TransplantationLiver Diseases

Outcome Measures

Primary Outcomes (1)

  • Incidence of biliary complications

    Statistical analyses are conducted to determine the incidence of biliary complication.

    within 10 years post-transplantation

Interventions

living donor liver transplantationPROCEDURE

other intervention cannot be applied.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

the patients who underwent living donor liver transplantation

You may qualify if:

  • All adult patients who underwent LDLT at the study center from 2012 to 2022

You may not qualify if:

  • Pediatric patients, deceased donor recipients, multi-organ transplants.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Liver Diseases

Condition Hierarchy (Ancestors)

Digestive System Diseases

Study Officials

  • Seoung Hoon kim, MD, PhD

    National Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR INVESTIGATOR
PI Title
National Cancer Center, Korea

Study Record Dates

First Submitted

July 29, 2025

First Posted

August 5, 2025

Study Start

January 1, 2012

Primary Completion

December 31, 2022

Study Completion

July 1, 2025

Last Updated

August 5, 2025

Record last verified: 2025-07