Incidence, Risk Factors, and Risk Model of Acute Kidney Injury After Liver Transplantation
1 other identifier
observational
573
1 country
1
Brief Summary
The incidence of acute kidney injury after liver transplantation has been reported to be 17 to 95 percent, but no definite treatment has been reported yet. Therefore, it is important to identify and prevent reversible risk factors for acute kidney injury after liver transplantation. Previous studies have reported several preoperative clinical risk factors, but preoperative medication and intraoperative colloid administration and hemodynamic parameters have not been evaluated. Therefore, we attempt to evaluate perioperative risk factors and develop simplified clinical risk scoring model.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2014
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
March 4, 2014
CompletedFirst Posted
Study publicly available on registry
March 6, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2015
CompletedAugust 28, 2015
August 1, 2015
1.4 years
March 4, 2014
August 27, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
acute kidney injury as defined by RIFLE criteria
acute kidney injury as defined by RIFLE criteria
during 7 days after transplantation
Secondary Outcomes (4)
incidence of renal replacement therapy
during one month after transplantation
incidence of acute rejection of graft
during one month after transplantation
incidence of initial poor graft function
during one month after transplantation
incidence of retransplantation
during one month after transplantation
Other Outcomes (1)
Mortality
during one month, six month, one year
Study Arms (1)
liver transplantation
patients who underwent living donor liver transplantation during between 2007 and 2013
Interventions
Eligibility Criteria
patients who underwent living donor liver transplantation between 2010 and 2013
You may qualify if:
- Patients who underwent living donor liver transplantation between 2010 and 2013 in Samsung Medical Center
You may not qualify if:
- Incomplete data regarding pre- and postoperative creatinine and estimated Glomerular Filtration Rate
- patient who underwent retransplantation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Samsung Medical Center
Seoul, 135-710, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
March 4, 2014
First Posted
March 6, 2014
Study Start
January 1, 2014
Primary Completion
June 1, 2015
Study Completion
June 1, 2015
Last Updated
August 28, 2015
Record last verified: 2015-08