Table-Top Water Pitcher to Reduce Arsenic Exposure Among Well Users in New Hampshire

NCT07103356 | Recruiting

• 1 other identifier: STUDY00033185
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The goals of this clinical trial are to:

• Which factors facilitate or impede uptake, use, and sustainability of the intervention?
• Are household income and/or home ownership associated with sustained filter use? Participants will:
• Receive a free 12-cup water filter pitcher and cartridge replacements
• Use the pitcher filtration system, including replacement of filter cartridges, per manufacturer recommendations
• Collect and mail water and urine samples at baseline, 4 weeks, and 12 weeks
• Complete online questionnaires at baseline, 4 weeks, and 12 weeks

Conditions

Arsenic Poisoning; Environmental Exposure; Water-Related Diseases

Keywords

Arsenic; Private Well; Environmental Health; Filter

Outcome Measures

Primary Outcomes (6)

• Water arsenic concentrations

  Changes in water arsenic concentrations from baseline to week 4

  4 weeks

• Urinary arsenic concentrations

  Changes in urinary arsenic concentrations from baseline to week 4

  4 weeks

• Reach

  Number of participants who receive the water pitcher filtration system among all eligible individuals and demographics

  4 weeks

• Adoption

  Number of participants using the filtration system after receiving it; number of participants who intend to use the system after the study period ends; and demographics of participants who used the filtration system during the study period or intend to use it after the study period ends

  4 weeks

• Implementation

  % of participants who adhere to the intervention during the intervention period (Fidelity), including using the pitcher filtration system for all drinking and cooking water and changing filter cartridges as recommended (measured by questionnaire: at home, did you use the pitcher filtration system for all of your drinking water, more than half of your drinking water, half of your drinking water, less than half of your drinking water, or none of your drinking water AND did you use did you use the pitcher filtration system for all of your cooking water, more than half of your cooking water, half of your cooking water, less than half of your cooking water, or none of your cooking water)

  4 weeks

• Maintenance

  % of participants who continue to use the pitcher filtration system during the 8-week sustainability period when replacement filter cartridges are no longer provided (measured by questionnaire: at home, did you use the pitcher filtration system for all of your drinking water, more than half of your drinking water, half of your drinking water, less than half of your drinking water, or none of your drinking water AND did you use did you use the pitcher filtration system for all of your cooking water, more than half of your cooking water, half of your cooking water, less than half of your cooking water, or none of your cooking water)

  8 weeks

Study Arms (1)

Water Pitcher Filtration System

EXPERIMENTAL

Arm 1: All participants receive pitcher filter and three replacement filters

Behavioral: Water Pitcher Filtration System

Interventions

Water Pitcher Filtration System BEHAVIORAL

Table-top water pitcher filtration system

Water Pitcher Filtration System

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 years or older
• NH resident living in Merrimack or Belknap county
• Use a private water system as primary drinking water source
• Water arsenic \>5 micrograms/L upon testing
• Confirm would be primary person in home maintaining the provided pitcher filter

You may not qualify if:

• Use or plan to use a mitigation strategy to reduce exposure to arsenic-contaminated drinking water in the next 12 weeks

Sponsors & Collaborators

• Trustees of Dartmouth College: lead

Study Sites (1)

Geisel School of Medicine at Dartmouth

Lebanon, New Hampshire, 03756, United States

RECRUITING

MeSH Terms

Conditions

Arsenic Poisoning; Waterborne Diseases

Condition Hierarchy (Ancestors)

Heavy Metal Poisoning, Nervous System; Neurotoxicity Syndromes; Nervous System Diseases; Poisoning; Chemically-Induced Disorders; Infections

Central Study Contacts

Caitlin Howe, PhD

CONTACT

603-646-5419; caitlin.g.howe@dartmouth.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Epidemiology

Study Record Dates

• First Submitted: May 8, 2025
• First Posted: August 5, 2025
• Study Start: February 24, 2026
• Primary Completion (Estimated): August 31, 2027
• Study Completion (Estimated): August 31, 2027
• Last Updated: March 24, 2026

Record last verified: 2026-03

Locations

US (1)