NCT07092098

Brief Summary

This study aimed to investigate whether six weeks of tDCS combined with lower-limb resistance training could enhance motor learning in healthy young adults and examined the persistence of any observed benefits.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 20, 2025

Completed
Same day until next milestone

Study Start

First participant enrolled

July 20, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

July 29, 2025

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2025

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2025

Completed
Last Updated

July 29, 2025

Status Verified

July 1, 2025

Enrollment Period

2 months

First QC Date

July 20, 2025

Last Update Submit

July 27, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Sequence Reaction Time Task

    In this task, a white circle appears above one of four horizontally arranged white squares on the computer screen with black background. Participans were instructed to press the proper button on the response pad (buttons H, J, K, L) using the corresponding finger of the right hand (index finger for button H, middle finger for button J, ring finger for button K, and small finger for button L) when the white circle appeared at the left side, middle-left side, middle-right side, or right side of the computer screen, respectively. Each session consists of eight blocks, with each block comprising 120 trials.

    Motor learning was assessed at before intervention, after three and six weeks of intervention, and one week post-intervention.

Study Arms (4)

tDCS combined with resistance training

EXPERIMENTAL
Combination Product: tDCS combined with resistance training

Resistance training alone

EXPERIMENTAL
Behavioral: Resistance training

tDCS alone

EXPERIMENTAL
Device: tDCS

Sham tDCS

SHAM COMPARATOR
Device: sham tDCS

Interventions

Transcranial direct current stimulation combined with resistance training

tDCS combined with resistance training

low-limb resistance training

Resistance training alone
tDCSDEVICE

Transcranial direct current stimulation

tDCS alone
sham tDCSDEVICE

Sham transcranial direct current stimulation

Sham tDCS

Eligibility Criteria

Sexmale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • normal or corrected-to-normal vision
  • right-handed

You may not qualify if:

  • color blindness
  • color weakness
  • dyslexia
  • history of smoking
  • cardiovascular diseases
  • personal or family history of mental illness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Resistance TrainingTranscranial Direct Current Stimulation

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaElectric Stimulation TherapyConvulsive TherapyPsychiatric Somatic TherapiesBehavioral Disciplines and ActivitiesElectroshockPsychological Techniques

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 20, 2025

First Posted

July 29, 2025

Study Start

July 20, 2025

Primary Completion

September 30, 2025

Study Completion

October 1, 2025

Last Updated

July 29, 2025

Record last verified: 2025-07