NCT07086261

Brief Summary

Objective: To explore the effects of intermittent retrieval training on cognitive function, daily water intake, body weight, total body water, drinking problem behaviors in day care centers, and caregiver distress in day care centers for elderly people with dementia. Methods: This study adopted a quasi-experimental research design with two groups of pre- and post-tests. The sample was recruited by convenient sampling. The experimental group was intervened with the intermittent retrieval training program to perform relevant drinking training, 40 minutes each time, 3 times a week, for a total of 8 weeks of intervention measures, while the control group was carried out with routine care for general drinking. Both groups collected pre-test data before the intermittent retrieval training intervention program in the first week, and conducted post-test data tracking and analysis in the 4th and 8th weeks after the intervention activities. The research tools included basic attribute data sheet, Chinese version of cognitive ability screening test (CASI), daily water intake, average daily water intake and drinking problem behaviors in the past week, body fat scale for measuring weight and total body water content, and day care center caregiver burden assessment scale. It is expected that this research intervention measure can improve the behavior of elderly people with dementia to drink water independently.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 17, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 25, 2025

Completed
12 days until next milestone

Study Start

First participant enrolled

August 6, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2025

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2025

Completed
Last Updated

August 28, 2025

Status Verified

August 1, 2025

Enrollment Period

3 months

First QC Date

July 17, 2025

Last Update Submit

August 26, 2025

Conditions

Keywords

Alzheimer's DiseaseSpaced Retrieval TrainingWater, drinkingMemoryFluid intake

Outcome Measures

Primary Outcomes (3)

  • Cognitive function (CASI)

    Total number of questions: 25, The higher the score, the better, with a full score of 100, indicating better cognitive function. Taking high school graduates as an example, a score of 82 or more is considered normal, 78-81 is suspected of mild cognitive impairment, and less than 77 is considered suspected of dementia.

    10-20minute

  • Daily water intake and Drinking Problem Behavior

    Calculate the water requirement of the elderly according to the recommended daily water requirement per person by multiplying 30 mL per kilogram of body weight (e.g., if the elderly weigh 60 kg, 60 kg Ă— 30 ml = 1800 ml, 1800 ml/day). While the elderly are at the day care center, researchers and staff will monitor their water intake. When they return home from the center, researchers will give each person a 600ml bottle of mineral water (the bottle will be marked with the total amount of water the elderly need to drink in a day). Elderly people are asked to take it home, and family members are asked to help monitor the elderly's water intake at home. Family members are asked to deduct the amount of water they drink and record the remaining amount of water in the "Elderly Drinking Water Good Health Plan Water Drinking Registration Form"and"Daily Water Intake Registration Form for Elderly People"

    From intervention to end of 8 weeks

  • Distress of caregivers in day care centers

    There are 10 questions in total, used in the questionnaire on the concerns of caregivers about drinking water problems of elderly people with dementia.The scale is a Likert scale with a 0-4 point scale, with a total of 40 points.The higher the score, the more trouble the caregiver has with the subject's drinking behavior.

    From intervention to end of 8 weeks

Study Arms (2)

Experimental Group

EXPERIMENTAL

Intervention of timed retrieval training program to implement relevant water drinking training

Other: Spaced Retrieval Training

Drink water as usual

NO INTERVENTION

Interventions

This study adopted a quasi-experimental research design with two groups of pre- and post-tests. The sample was recruited by convenient sampling. The experimental group used the time extraction training program to intervene and perform relevant water drinking training, 40 minutes each time, 3 times a week, for a total of 8 weeks of intervention measures, while the control group used routine care for general water drinking. Both groups collected pre-test data before the time extraction training intervention program activities in the first week, and conducted post-test data tracking and analysis in the 4th and 8th weeks after the intervention activities.

Experimental Group

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Elderly people with dementia aged 65 years or above who are receiving care in day care centers.
  • Clear consciousness and able to communicate in Mandarin and Taiwanese.
  • Clinical Dementia Rating Scale (CDR) should be 1-2 points.
  • Brain Health Test (BHT) should be less than 9 points.
  • Pass the SRT training screening test, indicating that the trainer's name can be remembered for 20-30 seconds.
  • Agree to participate in this study.

You may not qualify if:

  • Patients diagnosed with severe cognitive impairment according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) after evaluation by psychiatrists.
  • Patients with chronic heart disease and renal failure.
  • Patients with upper and lower limb dysfunction.
  • Patients with hearing impairment and dysphagia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Taoyuan Branch, Taipei Veterans General Hospital.

Taoyuan District, 330, Taiwan

Location

Related Publications (5)

  • Han JW, Son KL, Byun HJ, Ko JW, Kim K, Hong JW, Kim TH, Kim KW. Efficacy of the Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training (USMART) program among patients with mild cognitive impairment: a randomized controlled crossover trial. Alzheimers Res Ther. 2017 Jun 6;9(1):39. doi: 10.1186/s13195-017-0264-8.

    PMID: 28587629BACKGROUND
  • Kao CC, Lin LC, Wu SC, Lin KN, Liu CK. Effectiveness of different memory training programs on improving hyperphagic behaviors of residents with dementia: a longitudinal single-blind study. Clin Interv Aging. 2016 May 23;11:707-20. doi: 10.2147/CIA.S102027. eCollection 2016.

    PMID: 27307717BACKGROUND
  • Bunn DK, Abdelhamid A, Copley M, Cowap V, Dickinson A, Howe A, Killett A, Poland F, Potter JF, Richardson K, Smithard D, Fox C, Hooper L. Effectiveness of interventions to indirectly support food and drink intake in people with dementia: Eating and Drinking Well IN dementiA (EDWINA) systematic review. BMC Geriatr. 2016 May 4;16:89. doi: 10.1186/s12877-016-0256-8.

    PMID: 27142469BACKGROUND
  • Wu HS, Lin LC, Wu SC, Lin KN, Liu HC. The effectiveness of spaced retrieval combined with Montessori-based activities in improving the eating ability of residents with dementia. J Adv Nurs. 2014 Aug;70(8):1891-901. doi: 10.1111/jan.12352. Epub 2014 Jan 20.

    PMID: 24444172BACKGROUND
  • Wu HS, Lin LC, Su SC, Wu SC. The effects of spaced retrieval combined with errorless learning in institutionalized elders with dementia: recall performance, cognitive status, and food intake. Alzheimer Dis Assoc Disord. 2014 Oct-Dec;28(4):333-9. doi: 10.1097/WAD.0000000000000028.

    PMID: 24632986BACKGROUND

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 17, 2025

First Posted

July 25, 2025

Study Start

August 6, 2025

Primary Completion

November 1, 2025

Study Completion

November 30, 2025

Last Updated

August 28, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, ICF, CSR

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