Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy

NCT07079254 | Recruiting

• 1 other identifier: 2023-00059-01
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 2

Brief Summary

The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces. In doing so, it helps protect the joint from osteoarthritis - a form of joint failure commonly referred to as "joint wear". Meniscal surgeries are among the most common orthopaedic procedures performed both in Sweden and globally. Historically, damaged menisci were treated by removing the injured part. However, this approach is linked to early-onset osteoarthritis. Osteoarthritis affects approximately one-third of individuals over the age of 45 and ranks among the ten most common diagnoses in Europe based on years lived with disability. The knee is the most frequently affected joint, and the importance of the menisci in preserving knee function has become increasingly recognized. In recent years, advances in surgical techniques have led to a shift towards meniscus-preserving procedures. A typical injury is the displaced meniscus, in which a large portion of the meniscus becomes detached from the joint capsule and wedges itself inside the joint, causing mechanical locking and preventing full extension. A displaced meniscus often loses its blood supply and suffers mechanical damage from being compressed between the joint surfaces. To preserve the meniscus and prevent irreversible damage, early surgical intervention is required. If the injury is too old or the tissue too damaged, the injured part of the meniscus must be removed, which significantly increases the risk of developing early knee osteoarthritis. It remains unclear how soon surgery must be performed to successfully preserve the meniscus, and this likely depends on various other factors, including patient age, presence of additional joint injuries, and surgical technique. There is currently no reliable data on the proportion of displaced menisci that heal after meniscus-preserving surgery. However, studies suggest that 20-30% of repaired menisci require reoperation due to failed healing. Given that displaced menisci are considered surgical emergencies, they pose a significant burden on healthcare systems already strained by limited access to urgent surgery. Meanwhile, ongoing development of surgical techniques raise ethical and logistical questions for health providers - especially as the scientific evidence for the benefits of some advanced treatments remains inconclusive. Therefore, more research is needed to guide the optimal management of displaced bucket-handle lesions across a diverse patient population, taking into account age, activity level, and concurrent injuries. A key priority is to identify predictors of healing potential, particularly the time window during which surgical repair remains a viable option. With better knowledge, more menisci could potentially be preserved - reducing both the number of unnecessary re-operations and the long-term incidence of knee osteoarthritis.

Conditions

Meniscus Rupture; Meniscus Injury; Osteoarthritis of Knee

Keywords

Meniscus; Re-operation; Bucket-handle; Osteoarthritis

Outcome Measures

Primary Outcomes (1)

• Re-operation

  Re-operation for meniscus injury/lesion

  2-10 years

Secondary Outcomes (2)

• Knee Injury and Osteoarthritis Outcome Score (KOOS)

  From 6 months to 10 years

• Osteoarthritis in the knee

  10 years

Interventions

Meniscus suture PROCEDURE

The meniscus bucket-handle injury will either be treated with meniscus suture or partial meniscectomy

Partial meniscectomy PROCEDURE

The meniscus bucket-handle injury wil be treated with either meniscus suture or partial meniscectomy

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who present to the emergency department or the orthopaedic outpatient clinics at our hospitals with a knee extension deficit after trauma, with a clinically suspected bucket-handle meniscus rupture, are referred to a magnetic resonance imaging (MRI) within a week. Patients with a bucket-handle tear on the MRI, and no younger than 15 years, will be invited to participate in the study. Recruitment takes place at the outpatient clinic at the orthopaedic department at Skåne University Hospital in Malmö and the orthopaedic department at Hässleholm hospital.

You may qualify if:

• years or above.
• Displaced longitudinal bucket-handle tear including the posterior horn on MRI and a knee extension deficit.

You may not qualify if:

• Patient younger than 15 years.
• Insufficient knowledge of the Swedish language.
• Per-operative findings including a bucket-handle rupture in combination with a complete radial rupture

Sponsors & Collaborators

• Region Skane: lead

Study Sites (2)

Region Skåne, Orthopaedic department Kristianstad/Hässleholm

Hässleholm, Skåne County, Sweden

RECRUITING

Region Skåne, Skåne University Hospital

Malmo, Skåne County, Sweden

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Knee; Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Ola Svejme, MD, PhD

  Lund University, Department of Orthopaedics, Clinical Sciences, Malmö, Sweden

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sofie Alerskans, MD

CONTACT

+46 768-487639; sofie.alerskans@med.lu.se

Ola Svejme, MD, PhD

CONTACT

+46 722-106158; ola.svejme@skane.se

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 13, 2025
• First Posted: July 22, 2025
• Study Start: October 7, 2023
• Primary Completion (Estimated): December 1, 2035
• Study Completion (Estimated): December 1, 2045
• Last Updated: July 25, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

SE (2)