Cheers Health Restore Study

NCT07069608 | Not Yet Recruiting

• 1 other identifier: 1002
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

This observational cohort study, sponsored by Cheers Health and conducted by Principal Investigator Dr. Nirav Shah, aims to evaluate the potential role of Cheers Restore in supporting sleep quality, physiological recovery, and next-day well-being following alcohol consumption in healthy adults. Over a 6 week period, the study will utilize wearable devices and self-reported outcomes captured via the Alethios platform to assess real-world responses to use of Cheers Restore. Outcomes will be compared across three behavioral conditions: (1) alcohol consumption followed by Cheers Restore use, (2) alcohol-only nights without use of Cheers Restore, and (3) non-drinking nights.

Conditions

Sleep; Alcohol Aftereffects; Recovery

Keywords

alcohol use; wellness

Outcome Measures

Primary Outcomes (1)

• Sleep Quality

  Sleep quality, as measured by wearables such as Fitbit, Garmin and Oura rings (time spent in sleep stages, wakeup events, sleep onset).

  6 weeks

Secondary Outcomes (2)

• Alcohol Consumption Behavior

  6 weeks

• Heart Rate Variability

  6 weeks

Interventions

Cheers Restore DIETARY_SUPPLEMENT

Cheers Restore contains a formulation of antioxidants, electrolytes, and plant-based compounds designed to support physiological resilience and sleep recovery after alcohol consumption. This study is structured to evaluate Cheers Restore in a real-world setting without introducing investigational or therapeutic claims.

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This is a decentralized, 6 week observational cohort study conducted via the Alethios platform with approximately 100 participants.

You may qualify if:

• Adults aged 21 years or older
• Regular alcohol consumers (defined as ≥1 drinking night per week)
• Ownership of and willingness to use a wearable device compatible with the Alethios platform (e.g., Fitbit, Apple Watch, Oura)
• Ability and willingness to log alcohol consumption, Cheers Restore usage, and complete daily and weekly surveys via smartphone or web
• Willingness to use Cheers Restore during the study period when consuming alcohol
• English-speaking, capable of understanding informed consent

You may not qualify if:

• AUDIT-C score above gender-specific thresholds for hazardous drinking (≥4 for men, ≥3 for women)
• History of alcohol use disorder or prior treatment for substance misuse
• Routine binge drinking (≥5 drinks/occasion for men, ≥4 for women)
• Use of confounding substances:
• THC (any form)
• Recreational drugs
• Prescription stimulants, sedatives, or sleep aids
• Diagnosed sleep or psychiatric conditions known to impair sleep quality (e.g., insomnia, obstructive sleep apnea, restless legs syndrome, narcolepsy, major depressive disorder, post-traumatic stress disorder, bipolar disorder, schizophrenia, attention deficit/hyperactivity disorder)
• Pregnancy or breastfeeding
• Anticipated travel or scheduling conflicts disrupting normal sleep/alcohol routines
• Inability to comply with platform-based data collection requirements

Sponsors & Collaborators

• Cheers Health: lead
• Alethios, Inc.: collaborator

Related Links

• Cheers Restore Observational Study Landing Page and Eligibility Questionnaire

MeSH Terms

Conditions

Alcohol Drinking

Condition Hierarchy (Ancestors)

Drinking Behavior; Behavior

Central Study Contacts

Nirav Shah, MD

CONTACT

(650) 206-8006; nirav@investigator.alethios.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 18, 2025
• First Posted: July 16, 2025
• Study Start: July 15, 2025
• Primary Completion: August 30, 2025
• Study Completion: October 31, 2025
• Last Updated: July 16, 2025

Record last verified: 2025-07