Association Between Body Roundness Index and Wound Healing

NCT07065890 | Completed

• 1 other identifier: TJ-JRB202503009
• Study Type: observational
• Target: 422
• Locations: 1 country
• Sites: 1

Brief Summary

Background Obesity is a significant risk factor for adverse postoperative outcomes, including impaired wound healing. This study aimed to investigate the association between the Body Roundness Index (BRI) and impaired wound healing following thoracic surgery. Methods This study included 387 patients who underwent thoracic surgery at Tongji Hospital in Wuhan between October 2024 and January 2025. Wound healing was assessed 30 days postoperatively. Logistic regression and propensity score matching (PSM) analyses were performed to evaluate the relationship between BRI and impaired wound healing, with subgroup analyses conducted to further explore this association.

Conditions

Thoracic Surgery; Obesity; BMI; Visceral Fat; Wound Healing

Keywords

BRI; Thoracic Surgery; Wound Healing; BMI; Obesity

Outcome Measures

Primary Outcomes (1)

• Wound healing

  Determine the presence of impaired wound healing based on the definitions and guidelines for wound assessment and evaluation of healing.

  From the day of surgery to 30 days postoperatively

Study Arms (1)

impaired wound healing

This cohort include individuals diagnosed with poor wound healing according to the definitions and guidelines for assessment of wounds and evaluation of healing

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This prospective cohort study collected clinical data from patients undergoing thoracic surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between October 1, 2024, and January 30, 2025. Initial enrollment included 422 patients, with 387 participants retained after data cleaning.

You may qualify if:

• Patients who underwent surgical treatment in the Department of Thoracic Surgery at Tongji Hospital;
• Complete clinical data and diagnostic test results available;
• Postoperative follow-up conducted regularly in accordance with medical advice, with comprehensive follow-up records；

You may not qualify if:

• Without surgery or transferred to other departments；
• Missing basic information；
• Failure to review on time or refusal to follow up；
• Additional surgeries within 30 days of discharge from the hospital；

Sponsors & Collaborators

• Zhao bo: lead

Study Sites (1)

Tongji Medical College of HUST Tongji Medical College Tongji Hospital

Wuhan, Hubei, 430000, China

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Zhang q Zhang, Dr.

  Tongji Medical College of HUST Tongji Medical College Tongji Hospital

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 30 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: July 15, 2025
• Study Start: October 1, 2024
• Primary Completion: January 30, 2025
• Study Completion: May 1, 2025
• Last Updated: July 15, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)