Continuous Comprehensive Nursing for Post-CABG Recovery

NCT07062432 | Completed

• 1 other identifier: 2019-HBLS-ky038
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the effectiveness of a continuous comprehensive nursing (CCN) system compared to routine care for patients after coronary artery bypass graft (CABG) surgery. The primary goal is to determine if the CCN system improves postoperative hemoglobin levels. The study also investigates the effects on quality of life, mental health (anxiety and depression), red blood cell indices, immune markers, and patient satisfaction.

Conditions

Coronary Heart Disease (CHD)

Keywords

Continuous comprehensive nursing system; Coronary artery bypass surgery; Hemoglobin levels; Quality of life; Nursing Efficacy

Outcome Measures

Primary Outcomes (1)

• Change in Hemoglobin (Hb) Levels from Baseline to Day 7 Post-Surgery

  The change in hemoglobin concentration (g/L) was measured from the preoperative baseline value to the value at 7 days after the surgery. Venous blood samples were analyzed using an automatic biochemical analyzer.

  Baseline (preoperatively) and Day 7 post-surgery.

Secondary Outcomes (7)

• Change in Hemoglobin (Hb) Levels at Other Time Points

  Baseline, 12 hours, 72 hours, and 14 days post-surgery.

• Red Blood Cell Indices

  Day 7 post-surgery.

• Levels of Immune-Related Inflammatory Markers

  Day 7 post-surgery.

• Quality of Life (QoL)

  Day 14 post-surgery.

• Depressive Symptoms

  Day 14 post-surgery.

Study Arms (2)

Continuous Comprehensive Nursing (CCN) System

EXPERIMENTAL

Participants received a continuous comprehensive care plan delivered by specifically trained cardiac nurses. This plan included: * Preoperative Phase: Comprehensive education about the surgery, risks, and expected outcomes, along with psychological support. * Intraoperative Phase: Standard intraoperative nursing care including close monitoring. * Postoperative Inpatient Phase: In addition to routine care, this phase focused on pain management, wound care, and individualized rehabilitation guidance. * Post-Discharge Continuous Phase (3 months): This phase included regular follow-up (monthly phone calls, one outpatient visit at 6 weeks), ongoing psychological support, continuous education (medication adherence, diet, activity), structured home-based rehabilitation training, and periodic evaluation of quality of life.

Behavioral: Continuous Comprehensive Nursing System

Routine Care

ACTIVE COMPARATOR

Participants received standard institutional postoperative care for CABG, which primarily focused on the inpatient period. Key elements included: * Monitoring of vital signs, consciousness, and peripheral circulation. * Management of respiratory tract patency and urinary catheters. * Hourly monitoring of drainage tubes initially. * Wound care and monitoring for bleeding. * Body temperature monitoring and oral care. * Guidance on progressing from liquid diets. * Standard discharge instructions without structured post-discharge follow-up.

Other: Routine Postoperative Care

Interventions

Continuous Comprehensive Nursing System BEHAVIORAL

A multi-faceted nursing plan delivered by trained cardiac nurses, extending from the preoperative phase to 3 months post-discharge. In addition to routine inpatient care, the intervention included: preoperative education and psychological support; postoperative individualized rehabilitation guidance; and a continuous post-discharge program. The post-discharge phase involved structured follow-up (monthly phone calls, one 6-week outpatient visit), ongoing psychological support, reinforcement of education on medication adherence, diet, and activity progression, and guidance on a structured home-based exercise program.

Continuous Comprehensive Nursing (CCN) System

Routine Postoperative Care OTHER

Standard institutional postoperative care for patients after Coronary Artery Bypass Graft (CABG) surgery. This care was primarily focused on the inpatient period and included monitoring of vital signs, wound and drainage tube management, respiratory and circulatory support, and progressive diet guidance. The care concluded with standard discharge instructions and did not include the structured, continuous, or extended follow-up provided to the intervention group.

Routine Care

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age between 18 and 70 years.
• Confirmed diagnosis of coronary heart disease and evidence of coronary artery illness requiring CABG.
• Ability to understand the purpose and procedures of the study.
• Willingness to sign the informed consent form.

You may not qualify if:

• Presence of serious complications such as unstable myocardial ischemia or significant arrhythmia.
• Severe lung diseases (e.g., chronic obstructive pulmonary disease GOLD stage III/IV).
• Severe kidney diseases (e.g., chronic kidney disease Stage 4/5).
• Significantly impaired left ventricular ejection fraction (EF \< 30%).
• Concurrent participation in other clinical trials or receiving other interventions.
• Presence of severe mental illnesses or cognitive impairments.

Sponsors & Collaborators

• The First Hospital of Hebei Medical University: lead

Study Sites (1)

The First Hospital of Hebei Medical University

Shijiazhuang, Hebei, 050000, China

Location

MeSH Terms

Conditions

Coronary Disease

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: July 14, 2025
• Study Start: February 1, 2020
• Primary Completion: March 31, 2022
• Study Completion: June 30, 2022
• Last Updated: July 14, 2025

Record last verified: 2025-07

Locations

CN (1)