Acute Effects of Inspiratory Muscle Load on Diaphragmatic Recovery in Athletes

NCT07046637 | Not Yet Recruiting

• 1 other identifier: 020
• Study Type: interventional
• Target: 38
• Locations: 0 countries
• Sites: N/A

Brief Summary

This randomized controlled trial investigates the acute effects of inspiratory muscle warm-up and fatigue on diaphragmatic function in professional basketball players. Using ultrasound imaging and maximal inspiratory pressure (PIM) assessment, the study evaluates changes in diaphragmatic thickness and respiratory strength before and after specific inspiratory muscle loading protocols. Findings aim to clarify the short-term impact of these interventions on diaphragmatic recovery capacity, with potential implications for respiratory training, performance enhancement, and injury prevention strategies in elite athletic populations.

Conditions

Sports Physical Therapy; Athletic Injuries; Healthy

Outcome Measures

Primary Outcomes (1)

• Maximal inspiratory pressure

  It will be assessed using a Breathare MIP/MEP® (GH Innotek Co., Ltd., Busan, Republic of Korea).The Breathare MIP/MEP® is likely a respiratory pressure meter or manometer designed for measuring respiratory muscle strength. It typically includes a mouthpiece connected to a pressure sensor, and the device measures the force or pressure generated during respiratory maneuvers. The person will be instructed to take a maximal deep breath in, and then exhale to residual volume. After that, they will be asked to inhale forcefully against the resistance provided by the Breathare MIP/MEP®. This measures the strength of the inspiratory muscles. The measures will be expressed in cmH2O.

  Immediately before intervention, immediately after intervention, 15 minutes post intervention and 30 minutes post intervention

Secondary Outcomes (1)

• Diaphragmatic thickness and thickening fraction

  Immediately before intervention, immediately after intervention, 15 minutes post intervention and 30 minutes post intervention

Study Arms (2)

Inspiratory muscle fatigue group

EXPERIMENTAL

The EG (experimental group) will perform the diaphragmatic fatigue protocol using a specific inspiratory endurance test, in which volunteers, one-on-one, and in a single session, will breathe against submaximal inspiratory loads equivalent to 60% of their MIP (Maximum Inspiratory Pressure) through a threshold valve device. The participants will follow a free pattern of breathing until they are unable to establish flow during at least 3 maximum inspiratory efforts.

Device: Inspiratory muscle fatigue group

Inspiratory muscle warm-up group

ACTIVE COMPARATOR

The inspiratory muscle warm-up group will perform the protocol of 2 sets of 30 repetitions at 40% of their MIP, one-on-one, and in a single session, breathing against submaximal inspiratory loads using a threshold valve device. The participants will follow a free pattern of breathing until complete the protocol.

Device: Inspiratory muscle warm-up group

Interventions

Inspiratory muscle fatigue group DEVICE

The subjects will perform deep inspirations against a threshold device with varying resistances

Also known as: Inspiratory muscle fatigue

Inspiratory muscle fatigue group

Inspiratory muscle warm-up group DEVICE

The subjects will perform deep inspirations against a threshold device with varying resistances

Also known as: Inspiratory muscle warm-up

Inspiratory muscle warm-up group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male and female professional basketball players aged between 18 and 35 years.
• Holding a valid federation license at the autonomous or higher competitive level.
• A minimum of 3 consecutive seasons of competition in official FEB, FIBA, or equivalent regional leagues.
• Regular training frequency of ≥4 sessions per week over the past 6 months.
• No previous experience with inspiratory muscle training.
• Ability to understand study procedures and provide written informed consent.

You may not qualify if:

• History of chronic respiratory, neuromuscular, or cardiovascular disease.
• Musculoskeletal injury limiting inspiratory effort or physical participation (current or within the past three months).
• Previous thoracic or abdominal surgery.
• Current smokers.
• Use of pharmacological treatments that could affect respiratory or muscular function.
• Participation in another interventional study within the past 4 weeks.
• Inability to understand or follow study instructions.
• Tympanic membrane perforation or middle/inner ear pathology.
• Pregnancy or postpartum period within the last 6 months.

Sponsors & Collaborators

• Sierra Varona SL: lead
• Universidad Francisco de Vitoria: collaborator

Related Publications (1)

• Ladrinan-Maestro A, Sanchez-Infante J, Rodriguez-Sanz D, Sanchez-Sierra A. Short-term effects of inspiratory muscle warm-up and fatigue on diaphragmatic function in professional basketball players: a randomized clinical trial. Eur J Appl Physiol. 2026 Jan 6. doi: 10.1007/s00421-025-06116-2. Online ahead of print.

  PMID: 41493585 DERIVED

MeSH Terms

Conditions

Athletic Injuries

Condition Hierarchy (Ancestors)

Wounds and Injuries

Central Study Contacts

Arturo Ladriñan, PhD

CONTACT

925 26 88 00; arturo.ladrinan@uclm.es

eva V sanz

CONTACT

925 23 10 52

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Single-blind
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 29, 2025
• First Posted: July 1, 2025
• Study Start: July 10, 2025
• Primary Completion: August 5, 2025
• Study Completion: August 12, 2025
• Last Updated: July 3, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share