Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia

NCT07037979 | Completed DMC

• 1 other identifier: 2025ZW02
• Study Type: observational
• Target: 97
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate the correlation of Sarcopenia Parameters and Peripheral Artery Disease with chronic limb threatening ischaemia.

Conditions

Sarcopenia; Peripheral Arterial Disease; Chronic Limb Threatening Ischemia

Outcome Measures

Primary Outcomes (2)

• psoas muscle area (PMA) [measured by computed tomography (CT)]

  psoas muscle area (PMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level

  2023.1.1～2024.12.31

• total abdominal muscle area (TAMA) measured by computed tomography (CT)

  total abdominal muscle area (TAMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level

  2023.1.1～2024.12.31

Study Arms (1)

patiets with peripheral artery disease

Other: Not applicable- observational study

Interventions

Not applicable- observational study OTHER

non-applicable

patiets with peripheral artery disease

Eligibility Criteria

• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients of Peripheral Artery Disease

You may qualify if:

• Patients of Peripheral Artery Disease, including intermittent claudication and Chronic Limb Threatening Ischemia;
• Patients with Rutherford grade 2-6 between Jan.1 2023 and Dec.31 2024;
• Patients at age 18-80;
• Patients underwent an in-hospital routine enhanced whole abdomen to lower extremities CT scan;
• Patients able to complete the clinical follow-up for 3 months.

You may not qualify if:

• Poor CT quality or incomplete images;
• Incomplete clinical data;
• In-hospital mortality during Jan.1 2023 and Dec.31 2024.

Sponsors & Collaborators

• Fudan University: lead

Study Sites (1)

Huadong Hospital, Fudan University

Shanghai, 200040, China

Location

MeSH Terms

Conditions

Sarcopenia; Peripheral Arterial Disease; Chronic Limb-Threatening Ischemia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Atherosclerosis; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases; Peripheral Vascular Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Ischemia

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Hospital director

Study Record Dates

• First Submitted: June 5, 2025
• First Posted: June 26, 2025
• Study Start: January 1, 2023
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: June 26, 2025

Record last verified: 2025-06

Locations

CN (1)