Vestibular Function in Obesity

NCT07033221 | Recruiting

• 1 other identifier: 60/2025
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Previous studies have demonstrated that obesity negatively affects the human vestibular system. However, whether improvement in vestibular function occurs following the resolution of obesity remains an area requiring further investigation. Therefore, the investigators aimed to assess and analyze vestibular system functions in patients scheduled for bariatric surgery, both before the surgery, after the surgery, and following significant weight loss. Participants aged between 18 and 60 years who meet the inclusion criteria will be enrolled in the study. Initially, participants will undergo medical history assessment and Body Mass Index (BMI) measurement. The enrolled participants will be evaluated using the following tests at three different time points-preoperatively, at the 1st month postoperatively, and at the 6th month postoperatively: Video Head Impulse Test (vHIT), static posturography test, Berg Balance Scale, SF-12 Quality of Life Scale, and the Activity-specific Balance Confidence (ABC) Scale. Although obesity has been shown to be associated with impaired postural balance, studies evaluating the direct effect of BMI on postural sway are limited. The aim of our study is to assess the vestibular system in obese patients before and after bariatric surgery. Through this, the investigators hope to contribute to the literature by providing balance assessments in individuals with obesity

Conditions

Obesity; Vestibular Function Disorder; Balance Assessment; Balance Impairment; Sleeve Gastrectomy

Keywords

sleeve gastrectomy; balance in obese patients; vestibular function after sleeve gastrectomy; vestibulopathy in and obesity

Outcome Measures

Primary Outcomes (2)

• Change in Vestibular Function as Measured by Video Head Impulse Test (vHIT)

  The vHIT assesses semicircular canal function by recording eye movements in response to brief, passive head rotations.

  12 months

• Change in Balance Performance Using Static Posturography

  Objective measurement of postural sway and stability using a force platform system under various sensory conditions.

  12 months

Secondary Outcomes (3)

• Change in Functional Balance Measured by Berg Balance Scale (BBS)

  12 months

• Change in Quality of Life as Measured by the SF-12 Health Survey

  12 months

• Change in Balance Confidence Measured by the Activity-specific Balance Confidence (ABC) Scale

  12 months

Other Outcomes (1)

• Obesity Status: Height, Weight, and Body Mass Index (BMI)

  12 months

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Participants to be included in the study will be reached from patients who have applied to our hospital due to morbid obesity and are planned to undergo bariatric surgery in our hospital. Participants who meet the inclusion criteria and sign the Informed Voluntary Consent Form will be included in the study.

You may qualify if:

• The native language must be Turkish
• The participant must be between the ages of 18-60
• The participant must be suitable for bariatric surgery (BMI ≥40 kg/m2)
• Not have any previous vestibular diagnosis
• Not have any problems such as joints, muscles, or walking

You may not qualify if:

• Individuals with additional disabilities, neurological problems, vestibulopathy, joint, muscle or walking disorders will not be included in the study.

Sponsors & Collaborators

• Istanbul Aydın University: lead

Study Sites (1)

Istanbul Aydin University Faculty of Medicine

Istanbul, Küçükçekmece, 34295, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Obesity; Vestibular Diseases

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Labyrinth Diseases; Ear Diseases; Otorhinolaryngologic Diseases

Central Study Contacts

Dastan Temirbekov, Assistant professor

CONTACT

5314013014; dasekeeee@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: May 24, 2025
• First Posted: June 24, 2025
• Study Start: April 5, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: June 24, 2025

Record last verified: 2025-06

Locations

TU (1)