Comparison of Short- and Long-term Outcomes Between Robotic and Laparoscopic Hemicolectomy of Right Colon Cancer : A Multicenter Propensity Score Matching Analysis

NCT07029464 | Not Yet Recruiting DMC

• 1 other identifier: IITS2025462
• Study Type: observational
• Target: 4,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

This is a retrospective, multicenter cohort study to compare short- and long-term outcomes between robotic and laparoscopic hemicolectomy of right colon cancer.

Conditions

Robotic Surgical Procedures; Right Colon Tumors; Cancer; Laparoscopic Abdominal Surgery

Keywords

right colon cancer; robotic surgery

Outcome Measures

Primary Outcomes (1)

• 3-year overall survival (OS) rate and 3-year disease-free survival (DFS) rate

  （OS）From post-operation until death or the 3-year study endpoint （DFS）From post-operation to tumor recurrence or the 3-year study endpoint

Secondary Outcomes (10)

• Operative time

  Periprocedural

• Intraoperative blood loss

  Periprocedural

• Time to first flatus/bowel movement

  Periprocedural

• Time to liquid diet initiation

  Periprocedural

• Time to ambulation

  Periprocedural

Study Arms (2)

R Group

robotic surgery

L Group

Laparoscopic surgery

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The procedures were performed by 16 surgeons from 16 participating centers. Both primary surgeons and assistants completed standardized training in robotic and laparoscopic surgical techniques and obtained certification. Each center performs over 100 robotic- or laparoscopic-assisted radical right hemicolectomies annually. Primary surgeons had performed at least 50 cases of both robotic and laparoscopic-assisted radical right hemicolectomy.

You may qualify if:

• Underwent radical right hemicolectomy by Da Vinci robotic or laparoscopic surgery 2.Postoperative pathology confirmed right colon adenocarcinoma (pT2-T4aNxM0; including cecal adenocarcinoma, ascending colon adenocarcinoma, hepatic flexure colon adenocarcinoma, and proximal transverse colon adenocarcinoma) 3.Complete clinical data and pathological results available

You may not qualify if:

• Received neoadjuvant therapy prior to surgery 2.History of other malignancies in the past 5 years (except cured cervical carcinoma in situ, basal cell carcinoma, or squamous cell carcinoma of the skin) 3.Distant metastases (e.g., liver, lung) or extensive abdominal/pelvic metastases confirmed by contrast-enhanced CT, PET-CT, or intraoperative exploration 4.Comorbid neurological/psychiatric disorders impairing ability to express informed consent 5.Poor systemic condition with contraindications to general anesthesia 6.Severe obesity (BMI \>35 kg/m²) 7.Severe widespread abdominal adhesions precluding safe pneumoperitoneum establishment 8.Emergency surgery due to tumor perforation or obstruction 9.Refusal to provide informed consent

Sponsors & Collaborators

• The First Affiliated Hospital of Nanchang University: lead
• Cancer Institute and Hospital, Chinese Academy of Medical Sciences: collaborator
• Fudan University: collaborator
• The Second Affiliated Hospital of Harbin Medical University: collaborator
• Three Gorges Hospital of Chongqing University: collaborator
• The Affiliated Hospital of Qingdao University: collaborator
• The First Affiliated Hospital of Zhengzhou University: collaborator
• Tianjin Third Central Hospital: collaborator
• Shandong University Second Hospital: collaborator
• Nanfang Hospital, Southern Medical University: collaborator
• Huadong Hospital: collaborator
• Second Affiliated Hospital, School of Medicine, Zhejiang University: collaborator
• Second Xiangya Hospital of Central South University: collaborator
• Jiangxi Provincial People's Hopital: collaborator
• Pingxiang People 's Hospital: collaborator
• Ganzhou City People's Hospital: collaborator

MeSH Terms

Conditions

Neoplasms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: chief physician

Study Record Dates

• First Submitted: May 26, 2025
• First Posted: June 19, 2025
• Study Start: June 1, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): May 1, 2027
• Last Updated: June 19, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share