Immediate Implant in Posterior Mandible Region

NCT07027904 | Not Yet Recruiting

• 1 other identifier: xenograft with (PRF)
• Study Type: interventional
• Target: 24
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to evaluate implant stability and Width bone after placement of immediate implant and Xenograft mixed with Hyaluronic acid or with Platelet-Rich Fibrin (PRF) at posterior mandible region

Conditions

Immediate Implant With Bone Graft

Outcome Measures

Primary Outcomes (1)

• Implant secondary stability

  Method of Measurement (Using the Osstell® Device.) -Unit of Measurement (ISQ)

  6 months

Secondary Outcomes (1)

• width bone

  immediate postoperative and at 6 months

Study Arms (2)

using xenograft as space filling material mixed with hyaluronic acid

ACTIVE COMPARATOR

the jumping space will packed using Xenograft (cur oss , Astro star) with particle size ranging from 0.25 to 1 mm and it will be mixed with hyaluronic acid

Device: Implant

xenograft (cur oss , Astro star ) mixed with Platelet-Rich Fibrin (PRF)

EXPERIMENTAL

the jumping space will packed using Xenograft (cur oss , Astro star) with particle size ranging from 0.25 to 1 mm and it will be mixed with Platelet-rich fibrin (PRF)

Device: Implant

Interventions

Implant DEVICE

The immediate implant was placed, and the surrounding cavity was filled with xenograft bone material, along with the application of hyaluronic acid or platelet-rich fibrin (PRF) to enhance healing and bone integration.

using xenograft as space filling material mixed with hyaluronic acid; xenograft (cur oss , Astro star ) mixed with Platelet-Rich Fibrin (PRF)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18 years.
• Both sexes.
• Cooperative and likely to maintain good dental health.
• Recent extraction multi roots.
• There is a bone between (2 or 3) mm at lest from the apex of the root.

You may not qualify if:

• Patients who had undergone previous extraction of all badly decayed teeth .
• Implant placement in both healed bone and at the extraction sites in the same procedure.
• Presence of any local or systemic factors that might contraindicate oral surgery.
• Poor oral hygiene.
• Conditions that complicate wound healing such as uncontrolled diabetes, smoking (10 cigarettes a day), pregnancy, a history of drug or alcohol abuse, and an inability or unwillingness to return for follow-ups after occlusal loading.

Sponsors & Collaborators

• WASIM MHD JEHAD HALABI: lead

MeSH Terms

Interventions

Mutagenesis, Insertional

Intervention Hierarchy (Ancestors)

Protein Engineering; Genetic Engineering; Genetic Techniques; Investigative Techniques; Mutation; Genetic Variation; Genetic Phenomena; Mutagenesis

Central Study Contacts

WASIM HALABI, MSc degree candidate

CONTACT

+201152922450; wasim.halabi@dentistry.cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Bachelor's Degree of Oral and Dental Medicine

Study Record Dates

• First Submitted: May 19, 2025
• First Posted: June 19, 2025
• Study Start: June 12, 2025
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): August 1, 2026
• Last Updated: June 19, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share