The Study of Personalized Health Check-up Programs and Standards for High-altitude Migrant Populations

NCT07018193 | Not Yet Recruiting

• 1 other identifier: PHC-high
• Study Type: observational
• Target: 300
• Locations: 0 countries
• Sites: N/A

Brief Summary

By using wearable devices to monitor and record the physiological data changes and health outcomes (incidence and severity of high-altitude illnesses) of high-altitude migrants at different stages (pre-entry, acute/chronic high-altitude phases, and de-acclimatization phase), and referencing previous cohort studies on high-altitude populations, the study aims to provide a basis for developing personalized health assessment protocols for high-altitude migrants. The formulated assessment protocols and standards will then be validated.

Conditions

High Altitude

Outcome Measures

Primary Outcomes (1)

• Rates of high altitude sickness and related diseases.

  Early diagnosis rates of acute and chronic altitude sickness and related diseases induced or aggravated by the plateau population in migrant plateau populations.

  through study completion, an average of 3 years

Study Arms (2)

Exploration group

200 participants, to explore and formulate and optimize personalized plans and standards for health examinations for people living in plateaus.

Verification group

100 participants, to verify the feasibility of the physical examination plan and its effectiveness in the early diagnosis of altitude sickness and plateau environment-related comorbidities.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Recruit those who live in plains and prepare to move to the plateau in the short term or medium term.

You may qualify if:

• Men and women aged ≥18;
• Those living in plains and preparing to move to the plateau for a short-term or medium-term period;
• Can understand the research requirements and be willing to sign a written informed consent form (ICF).

You may not qualify if:

• Past history of contraindicated plateau travel: such as advanced COPD (FEV₁\<30% of the expected value or requires continuous oxygen therapy), advanced cystic fibrosis (FEV₁\<30% of the expected value or requires continuous oxygen therapy), advanced restricted pulmonary disease (FEV₁\<50% of the expected value or requires continuous oxygen therapy), decompensated heart failure, high-risk pregnancy, myocardial infarction or stroke occurred within 90 days, poorly controlled epilepsy, pulmonary hypertension (PASP\>90mmHg), sickle cell anemia, unstable angina pectoris, high-risk cerebrovascular abnormalities that have not been treated, etc.

Sponsors & Collaborators

• Capital Medical University: lead

MeSH Terms

Conditions

Altitude Sickness

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases

Central Study Contacts

Yuan Wang, MD

CONTACT

+86-13581567815; wilma0106@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 12, 2025
• First Posted: June 12, 2025
• Study Start: June 30, 2025
• Primary Completion (Estimated): December 31, 2028
• Study Completion (Estimated): December 31, 2028
• Last Updated: June 12, 2025

Record last verified: 2025-05