Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery
PECUR
Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery
1 other identifier
observational
380
1 country
1
Brief Summary
Veno-vneous extracorporeal membrane oxygenation (VV-ECMO) is an established support strategy for acute respiratory failure, but its role in the perioperative management of emergency thoracic surgery remains poorly defined. This retrospective, multicenter, observational study aims to assess the clinical outcomes and prognostic factors in this high-risk population. Patients undergoing emergency thoracic procedures requiring VV-ECMO will be compared to a control cohort of patients treated with VV-ECMO for medical respiratory failure. Data will be collected from two French academic centers (CHU Amiens-Picardie and CHU Dijon).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2025
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 29, 2025
CompletedStudy Start
First participant enrolled
June 1, 2025
CompletedFirst Posted
Study publicly available on registry
June 12, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2026
CompletedJune 13, 2025
June 1, 2025
5 months
April 29, 2025
June 12, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
90-day all-cause mortality
90 days
Secondary Outcomes (2)
90-day mortality in oncologic vs. non-oncologic thoracic surgery
90 days
Postoperative complication rates
90 days
Study Arms (2)
VV-ECMO after emergency thoracic surgery
VV-ECMO after emergency thoracic surgery
VV-ECMO for medical ARF
VV-ECMO for medical indication
Eligibility Criteria
Adults ≥ 18 years, Patients undergoing emergency thoracic procedures requiring VV-ECMO and patients treated with VV-ECMO for medical respiratory failure.
You may qualify if:
- Adults ≥ 18 years
- VV-ECMO initiated during or after emergency thoracic surgery
- No opposition to data use
You may not qualify if:
- Pregnant women
- Veno-Arterial ECMO patients
- Patients under legal protection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHRU Amiens
Amiens, 80480, France
Related Publications (1)
Beyls C, Soulier-Zaninka Q, Georges O, Nguyen M, Dheilly T, Nicolas M, Huette P, De Dominicis F, Abou-Arab O, Guinot PG, Mahjoub Y. Perioperative Veno-Venous Extracorporeal Membrane Oxygenation in Non-Elective Thoracic Surgery: A Propensity-Matched Bicentric Comparison With Medical Indication. Interdiscip Cardiovasc Thorac Surg. 2025 Nov 6;40(11):ivaf255. doi: 10.1093/icvts/ivaf255.
PMID: 41134639DERIVED
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 29, 2025
First Posted
June 12, 2025
Study Start
June 1, 2025
Primary Completion
November 1, 2025
Study Completion
April 1, 2026
Last Updated
June 13, 2025
Record last verified: 2025-06
Data Sharing
- IPD Sharing
- Will not share