NCT06555107

Brief Summary

Studies evaluating postoperative pain as a risk factor for CPSP are almost exclusively carried out in the context of scheduled surgery. As a result, the preoperative pain studied as a risk factor for chronicity is essentially a state of pain that has persisted for several weeks or even several months. In emergency surgeries, patients are subject to acute preoperative pain of varying intensity and the duration of which may vary by a few days. A few studies have highlighted the intensity of acute preoperative pain as a factor favouring moderate to severe postoperative pain. At this point, no study has addressed the long-term consequences of this intense preoperative pain the emergency context. An evaluation in the field of emergency surgery, where the preoperative pain is often intense and limited in time, would enable us to identify more precisely the impact of acute pain on the incidence of CPSP. The investigators are hypothesising that the occurrence of CPSP at 3 months in patients undergoing emergency orthopaedic or abdominal surgery is associated with acute preoperative pain.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
693

participants targeted

Target at P75+ for not_applicable

Timeline
11mo left

Started Aug 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress65%
Aug 2024Apr 2027

First Submitted

Initial submission to the registry

August 13, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 15, 2024

Completed
14 days until next milestone

Study Start

First participant enrolled

August 29, 2024

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2027

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2027

Last Updated

January 16, 2026

Status Verified

January 1, 2026

Enrollment Period

2.3 years

First QC Date

August 13, 2024

Last Update Submit

January 15, 2026

Conditions

Chronic Postsurgical PainAcute PainEmergency SurgeryOpioidPostoperative PainRisk Factors

Keywords

risk factorsChronic Postsurgical PainAcute Painemergency surgeryopioidPostoperative Pain

Outcome Measures

Primary Outcomes (1)

  • Frequency of CPSP

    at 3 months

Interventions

questionnaireOTHER

Patients included in the study will be asked to complete a questionnaire 48 to 72 hours after surgery to assess their perception of pain and preoperative anxiety

phone callOTHER

Patients will then be interviewed by phone 3 months after their emergency surgery. During the interview, they will be questioned via a standardised questionnaire on the existence of CPSP

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥18 years old.
  • Emergency orthopaedic and/or abdominal surgery.
  • Informed consent.
  • Affiliation to a social security scheme

You may not qualify if:

  • Intraoperative complications that are life-threatening or require the surgical procedure to be discontinued.
  • Post-operative intensive care unit admission.
  • Ambulatory surgery.
  • Endoscopic surgery.
  • Repeat surgery at the same site in less that 3months.
  • Pregnant or breast-feeding patients.
  • Patients under guardianship or deprived of liberty.
  • Patients suffering from psychiatric pathologies.
  • Patients suffering from neurodegenerative pathologies.
  • Patients for whom self-assessment of pain using a numerical scale (0-10) cannot be carried out (non-communicative patients, non-French-speaking patients, and so on).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Amiens-Picardie

Amiens, 80054, France

RECRUITING

MeSH Terms

Conditions

Pain, PostoperativeAcute Pain

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Central Study Contacts

Paul TARPIN, Dr

CONTACT

0322087980Tarpin.Paul@chu-amiens.fr

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 13, 2024

First Posted

August 15, 2024

Study Start

August 29, 2024

Primary Completion (Estimated)

January 1, 2027

Study Completion (Estimated)

April 1, 2027

Last Updated

January 16, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)