NCT07016360

Brief Summary

This is a comparative study between two treatment options for skin viral infection.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
98

participants targeted

Target at P50-P75 for phase_4

Timeline
4mo left

Started Sep 2025

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress65%
Sep 2025Sep 2026

First Submitted

Initial submission to the registry

May 21, 2025

Completed
21 days until next milestone

First Posted

Study publicly available on registry

June 11, 2025

Completed
3 months until next milestone

Study Start

First participant enrolled

September 15, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 15, 2026

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 15, 2026

Expected
Last Updated

April 29, 2026

Status Verified

April 1, 2026

Enrollment Period

5 months

First QC Date

May 21, 2025

Last Update Submit

April 23, 2026

Conditions

Viral Warts

Keywords

Plantar wartsTopical adapalene gelCryotherapy

Outcome Measures

Primary Outcomes (1)

  • Efficacy of Treatment

    It will be defined through visual inspection by observing the complete clearance of the warts after 8 weeks administration of the treatment in both groups

    06 months

Study Arms (2)

A

EXPERIMENTAL

Treated with Topical adapalene gel 0.1%

Drug: Topical Adapalene Gel 0.1%

B

EXPERIMENTAL

Treated with liquid nitrogen over affected parts

Procedure: Topical Liquid Nitrogen application

Interventions

Topical Adapalene Gel 0.1%DRUG

Topical adapalene is a retinoid that helps in epidermal changes. Cryotherapy is a liquid nitrogen applied to affected parts for 6 months

A
Topical Liquid Nitrogen applicationPROCEDURE

Liquid Nitrogen will be applied to affected parts.

B

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients age limit 18-60 Years Patients with either gender (Male/Female) Patients with recurrent plantar warts

You may not qualify if:

  • Pregnancy/lactation. Pt on topical or systemic therapy in last 6 months. On immunosuppressants. \> 5 lesions. Pts with local secondary infections.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Khyber Teaching Hospital

Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan

RECRUITING

MeSH Terms

Conditions

Warts

Condition Hierarchy (Ancestors)

Papillomavirus InfectionsDNA Virus InfectionsVirus DiseasesInfectionsSkin Diseases, ViralTumor Virus InfectionsSkin Diseases, InfectiousSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Saba Naz, MBBS

    Khyber Teaching Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Saba Naz, MBBS

CONTACT

+923209600115sabikhattak477@gmail.com

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
DOCTOR

Study Record Dates

First Submitted

May 21, 2025

First Posted

June 11, 2025

Study Start

September 15, 2025

Primary Completion

February 15, 2026

Study Completion (Estimated)

September 15, 2026

Last Updated

April 29, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Patient's confidentiality may be breached

Locations

PA(1)