Effect of Locally Produced Mango Variety on Glycemic Index

NCT07015827 | Not Yet Recruiting

• 1 other identifier: GL/GI-NA_1V1
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

This randomized trial aims to assess the glycemic index (GI) of locally available mango varieties in healthy adult participants, using glucose as the reference food. The study will evaluate the postprandial blood glucose response elicited by selected mango varieties and compare it to the response produced by a standard glucose . The objective is to determine whether certain mango varieties have a lower glycemic impact, which may be relevant for dietary planning and public health recommendations.

Conditions

Glycemic Index and Glycemic Load

Keywords

Glycemic index; posprandial glucose response; glycemic load

Outcome Measures

Primary Outcomes (1)

• Glycemic Index (GI) of Mango Varieties

  Glycemic index will be calculated for each mango variety by measuring the postprandial blood glucose response over 120 minutes and comparing the incremental area under the curve (iAUC) to that of a standard glucose reference.

  0 to 120 minutes after consumption of test food

Secondary Outcomes (1)

• Peak Blood Glucose Level

  0 to 120 minutes after consumption

Study Arms (1)

Single group (cross over)

ACTIVE COMPARATOR

Participants will consume 50 grams of glucose solution. This serves as the reference food for calculating the glycemic index

Other: Mango (langra); Other: mango (chaunsa); Other: MANGO (SINDHRI)

Interventions

Mango (langra) OTHER

Participants will consume mango variety A . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast.

Single group (cross over)

mango (chaunsa) OTHER

Participants will consume mango variety B . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast.

Single group (cross over)

MANGO (SINDHRI) OTHER

Participants will consume mango variety C . The test food will provide 50 grams of available carbohydrates, and will be consumed after an overnight fast.

Single group (cross over)

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy non-diabetic adults
• Normal fasting blood glucose levels
• Willingness to provide informed consent

You may not qualify if:

• Diagnosis of diabetes mellitus or impaired glucose tolerance
• Gastrointestinal, metabolic, or endocrine disorders
• Current use of medications affecting blood glucose
• Pregnant or lactating women
• Smoking or alcohol consumption

Sponsors & Collaborators

• Rehman Medical Institute - RMI: lead

MeSH Terms

Interventions

Mangifera indica extract

Central Study Contacts

Naseer Ahmed

CONTACT

03305485960; dr.naseer99@mail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate proffessor

Study Record Dates

• First Submitted: June 3, 2025
• First Posted: June 11, 2025
• Study Start: June 1, 2025
• Primary Completion: August 1, 2025
• Study Completion: September 1, 2025
• Last Updated: June 11, 2025

Record last verified: 2025-06