Comparative Evaluation of Glycemic Index of Different Types of Jaggery Produced Locally in Pakistan

NCT07015814 | Not Yet Recruiting

• 1 other identifier: GL/GI-NA_1V2
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response.

Conditions

Glycemic Index and Glycemic Load

Keywords

glycemic index

Outcome Measures

Primary Outcomes (1)

• Glycemic Index (GI) of Different Types of Jaggery

  The incremental area under the blood glucose response curve (iAUC) over 2 hours after consumption of each type of jaggery, expressed as a percentage of the glucose reference.

  Measured at multiple time points post-consumption (e.g., 0, 15, 30, 45, 60, 90, and 120 minutes) during each test session.

Secondary Outcomes (1)

• Postprandial Blood Glucose Response Curve

  Same as primary outcome (0-120 minutes).

Study Arms (1)

Single group (cross over)

ACTIVE COMPARATOR

Participants will receive all test interventions (2 different varieties of jaggery and a glucose reference) in a randomized sequence with appropriate washout periods between each session. Blood glucose levels will be measured after each test food to determine and compare glycemic index values.

Other: Golden sugarcane jaggery; Other: Dark brown sugarcane jaggery

Interventions

Golden sugarcane jaggery OTHER

Participants will consume a standardized portion of jaggery Type A providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period.

Single group (cross over)

Dark brown sugarcane jaggery OTHER

Participants will consume a standardized portion of jaggery Type B providing 50 grams of available carbohydrates. Capillary blood glucose will be measured over a 2-hour postprandial period.

Single group (cross over)

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may not qualify if:

• \) Pregnant or lactating female participants, as well as any person with gastrointestinal, metabolic, or endocrine disease (e.g., thyroid disease, PCOS, IBD), will be excluded.
• \) Also, subjects with a history of recent acute illness (within the last 2 weeks) will be deferred.

Sponsors & Collaborators

• Rehman Medical Institute - RMI: lead

Study Sites (1)

Rehman Medical Institue

Peshawar, Khyber Pakhtunkhwa, 092, Pakistan

Location

Related Publications (3)

• Fats and oils in human nutrition. Report of a joint expert consultation. Food and Agriculture Organization of the United Nations and the World Health Organization. FAO Food Nutr Pap. 1994;57:i-xix, 1-147. No abstract available.

  PMID: 7641870 BACKGROUND

• International Diabetes Federation. (2021). *IDF Diabetes Atlas* (10th ed.). Brussels, Belgium: IDF.

  BACKGROUND

• Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981 Mar;34(3):362-6. doi: 10.1093/ajcn/34.3.362.

  PMID: 6259925 BACKGROUND

Central Study Contacts

Naseer Ahmed

CONTACT

03305485960; dr.naseer99@mail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 3, 2025
• First Posted: June 11, 2025
• Study Start: June 1, 2025
• Primary Completion: August 1, 2025
• Study Completion: September 1, 2025
• Last Updated: June 11, 2025

Record last verified: 2025-06

Locations

PA (1)