NCT07015567|RecruitingDMC

Treatment of Complex Post-traumatic Stress Disorder Among Displaced People in Switzerland and Germany

ESTAIR_REFUGEE

Contextualised, Culture-sensitive Diagnosis and Psychotherapy for the Treatment of Complex Post-traumatic Stress Disorder Among Displaced People in Switzerland and Germany: A Two-step Multicentric Randomised Clinical Trial

Eva Heim ClinicalTrials.gov

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2 other identifiers

BASEC 2025-0045010001G_212438

Study Type

interventional

Target

288

Locations

2 countries

Sites

Timeline

RegisteredJun 2025

StartedJan 2026

CompletionDec 2030

Brief Summary

In WHO ICD-11 (its latest edition), the diagnostic criteria for post-traumatic stress disorder (PTSD) were revised, and a new sibling disorder, complex post-traumatic stress disorder (CPTSD) was introduced. CPTSD is a debilitating condition associated with severe, prolonged, or chronic trauma. Refugee populations are affected by high prevalence of CPTSD because of high rates of such trauma (e.g. torture). Untreated CPTSD has negative consequences for quality of life and for integration into the host society. Evidence indicates cultural variation in the phenomenology of CPTSD. Modular approaches, e.g., the Skills Training in Affective and Interpersonal Regulation combined with Modified Prolonged Exposure (ESTAIR/MPE), have been recommended for the treatment of CPTSD. However, they have not been tested in a clinical trial among refugees so far and there are no available publications about their effectiveness in CPTSD symptom reduction among this population. Research suggests a higher symptom reduction of trauma-focused techniques, such as Narrative Exposure Therapy (NET), among refugee population. In a previous study, the investigators pilot tested a version of ESTAIR/NET that was adapted to sociocultural and structural aspects related to psychopathology in refugee populations. The performance of these culturally adapted modules in CPTSD symptom reduction among the refugee population remains to be assessed. The present clinical trial seeks to assess the effect of the culturally adapted modules of the ESTAIR manual on symptom reduction among refugees and asylum seekers diagnosed with CPTSD.

Trial Health

On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

288

participants targeted

Target at P75+ for not_applicable

Timeline

55mo left

Started Jan 2026

Longer than P75 for not_applicable

Geographic Reach

2 countries

7 active sites

Status

recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

4.9 years study duration

Study Progress6%

Jan 2026Dec 2030

First Submitted

Initial submission to the registry

June 3, 2025

Completed

8 days until next milestone

First Posted

Study publicly available on registry

June 11, 2025

Completed

7 months until next milestone

Study Start

First participant enrolled

January 21, 2026

Completed

4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2030

Expected

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2030

Last Updated

January 27, 2026

Status Verified

January 1, 2026

Enrollment Period

4.9 years

First QC Date

June 3, 2025

Last Update Submit

January 23, 2026

Conditions

Complex Post-Traumatic Stress Disorder

Keywords

Refugee populationsCultural adaptationFactorial experimentCulturally sensitive psychotherapy

Outcome Measures

Primary Outcomes (1)

CPTSD symptom change
CPTSD symptom change will be assessed with the International Trauma Questionnaire (ITQ-28). This questionnaire contains 28 items on symptoms that are self-rated on a Likert scale of 0-4, with a maximum total score of 112.
8 months

Secondary Outcomes (5)

Depression
8 months
Anxiety
8 months
Somatic symptoms
8 months
Well-being
8 months
Dissociative symptoms (Shut-D)
8 months

Study Arms (48)

1. Waiting period, emotion regulation, negative self-concept, interpersonal relationships

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

2. Waiting period, emotion regulation, negative self-concept, narrative exposure therapy

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

3. Waiting period, emotion regulation, interpersonal relationships, negative self-concept

EXPERIMENTAL

4. Waiting period, emotion regulation, interpersonal relationships, narrative exposure therapy

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

5. Waiting period, emotion regulation, narrative exposure therapy, negative self-concept

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

6. Waiting period, emotion regulation, narrative exposure therapy, interpersonal relationships

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

7. Waiting period, negative self-concept, emotion regulation, interpersonal relationships

EXPERIMENTAL

8. Waiting period, negative self-concept, emotion regulation, narrative exposure therapy

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

9. Waiting period, negative self-concept, interpersonal relationships, emotion regulation

EXPERIMENTAL

10. Waiting period, negative self-concept, interpersonal relationships, narrative exposure therapy

EXPERIMENTAL

Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

11. Waiting period, negative self-concept, narrative exposure therapy, emotion regulation

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

12. Waiting period, negative self-concept, narrative exposure therapy, interpersonal relationships

EXPERIMENTAL

13. Waiting period, interpersonal relationships, emotion regulation, negative self-concept

EXPERIMENTAL

14. Waiting period, interpersonal relationships, emotion regulation, narrative exposure therapy

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

15. Waiting period, interpersonal relationships, negative self-concept, emotion regulation

EXPERIMENTAL

16. Waiting period, interpersonal relationships, negative self-concept, narrative exposure therapy

EXPERIMENTAL

17. Waiting period, interpersonal relationships, narrative exposure therapy, emotion regulation

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

18. Waiting period, interpersonal relationships, narrative exposure therapy, negative self-concept

EXPERIMENTAL

19. Waiting period, narrative exposure therapy, emotion regulation, negative self-concept

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

20. Waiting period, narrative exposure therapy, emotion regulation, interpersonal relationships

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

21. Waiting period, narrative exposure therapy, negative self-concept, emotion regulation

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

22. Waiting period, narrative exposure therapy, negative self-concept, interpersonal relationships

EXPERIMENTAL

23. Waiting period, narrative exposure therapy, interpersonal relationships, emotion regulation

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

24. Waiting period, narrative exposure therapy, interpersonal relationships, negative self-concept

EXPERIMENTAL

25. Emotion regulation, negative self-concept, interpersonal relationships, waiting period

EXPERIMENTAL

26. Emotion regulation, negative self-concept, narrative exposure therapy, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

27. Emotion regulation, interpersonal relationships, negative self-concept, waiting period

EXPERIMENTAL

28. Emotion regulation, interpersonal relationships, narrative exposure therapy, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

29. Emotion regulation, narrative exposure therapy, negative self-concept, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

30. Emotion regulation, narrative exposure therapy, interpersonal relationships, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

31. Negative self-concept, emotion regulation, interpersonal relationships, waiting period

EXPERIMENTAL

32. Negative self-concept, emotion regulation, narrative exposure therapy, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

33. Negative self-concept, interpersonal relationships, emotion regulation, waiting period

EXPERIMENTAL

34. Negative self-concept, interpersonal relationships, narrative exposure therapy, waiting period

EXPERIMENTAL

35. Negative self-concept, narrative exposure therapy, emotion regulation, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

36. Negative self-concept, narrative exposure therapy, interpersonal relationships, waiting period

EXPERIMENTAL

37. Interpersonal relationships, emotion regulation, negative self-concept, waiting period

EXPERIMENTAL

38. Interpersonal relationships, emotion regulation, narrative exposure therapy, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

39. Interpersonal relationships, negative self-concept, emotion regulation, waiting period

EXPERIMENTAL

40. Interpersonal relationships, negative self-concept, narrative exposure therapy, waiting period

EXPERIMENTAL

41. Interpersonal relationships, narrative exposure therapy, emotion regulation, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

42. Interpersonal relationships, narrative exposure therapy, negative self-concept, waiting period

EXPERIMENTAL

43. Narrative exposure therapy, emotion regulation, negative self-concept, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

44. Narrative exposure therapy, emotion regulation, interpersonal relationships, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

45. Narrative exposure therapy, negative self-concept, emotion regulation, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

46. Narrative exposure therapy, negative self-concept, interpersonal relationships, waiting period

EXPERIMENTAL

47. Narrative exposure therapy, interpersonal relationships, emotion regulation, waiting period

EXPERIMENTAL

Behavioral: Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)Behavioral: Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)

48. Narrative exposure therapy, interpersonal relationships, negative self-concept, waiting period

EXPERIMENTAL

Interventions

Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)BEHAVIORAL

ESTAIR is a psychotherapeutic manual for the treatment of CPTSD. The manual was adapted to the target population. It contains 24 sessions which are organised in four modules, including a module about emotion regulation. This module contains exercises for emotional awareness and emotion regulation with different focuses (on body, thoughts and behaviour).

1. Waiting period, emotion regulation, negative self-concept, interpersonal relationships11. Waiting period, negative self-concept, narrative exposure therapy, emotion regulation13. Waiting period, interpersonal relationships, emotion regulation, negative self-concept14. Waiting period, interpersonal relationships, emotion regulation, narrative exposure therapy15. Waiting period, interpersonal relationships, negative self-concept, emotion regulation17. Waiting period, interpersonal relationships, narrative exposure therapy, emotion regulation19. Waiting period, narrative exposure therapy, emotion regulation, negative self-concept2. Waiting period, emotion regulation, negative self-concept, narrative exposure therapy20. Waiting period, narrative exposure therapy, emotion regulation, interpersonal relationships21. Waiting period, narrative exposure therapy, negative self-concept, emotion regulation23. Waiting period, narrative exposure therapy, interpersonal relationships, emotion regulation25. Emotion regulation, negative self-concept, interpersonal relationships, waiting period26. Emotion regulation, negative self-concept, narrative exposure therapy, waiting period27. Emotion regulation, interpersonal relationships, negative self-concept, waiting period28. Emotion regulation, interpersonal relationships, narrative exposure therapy, waiting period29. Emotion regulation, narrative exposure therapy, negative self-concept, waiting period3. Waiting period, emotion regulation, interpersonal relationships, negative self-concept30. Emotion regulation, narrative exposure therapy, interpersonal relationships, waiting period31. Negative self-concept, emotion regulation, interpersonal relationships, waiting period32. Negative self-concept, emotion regulation, narrative exposure therapy, waiting period33. Negative self-concept, interpersonal relationships, emotion regulation, waiting period35. Negative self-concept, narrative exposure therapy, emotion regulation, waiting period37. Interpersonal relationships, emotion regulation, negative self-concept, waiting period38. Interpersonal relationships, emotion regulation, narrative exposure therapy, waiting period39. Interpersonal relationships, negative self-concept, emotion regulation, waiting period4. Waiting period, emotion regulation, interpersonal relationships, narrative exposure therapy41. Interpersonal relationships, narrative exposure therapy, emotion regulation, waiting period43. Narrative exposure therapy, emotion regulation, negative self-concept, waiting period44. Narrative exposure therapy, emotion regulation, interpersonal relationships, waiting period45. Narrative exposure therapy, negative self-concept, emotion regulation, waiting period47. Narrative exposure therapy, interpersonal relationships, emotion regulation, waiting period5. Waiting period, emotion regulation, narrative exposure therapy, negative self-concept6. Waiting period, emotion regulation, narrative exposure therapy, interpersonal relationships7. Waiting period, negative self-concept, emotion regulation, interpersonal relationships8. Waiting period, negative self-concept, emotion regulation, narrative exposure therapy9. Waiting period, negative self-concept, interpersonal relationships, emotion regulation

Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)BEHAVIORAL

ESTAIR is a psychotherapeutic manual for the treatment of CPTSD. The manual was adapted to the target population. It contains 24 sessions which are organised in four modules, including a module about negative self-concept. In this module, the manual tackles topics such as what is the self, thinking about the self through cognitive restructuring, criticism and compassion and the self in relation to others.

1. Waiting period, emotion regulation, negative self-concept, interpersonal relationships10. Waiting period, negative self-concept, interpersonal relationships, narrative exposure therapy11. Waiting period, negative self-concept, narrative exposure therapy, emotion regulation12. Waiting period, negative self-concept, narrative exposure therapy, interpersonal relationships13. Waiting period, interpersonal relationships, emotion regulation, negative self-concept15. Waiting period, interpersonal relationships, negative self-concept, emotion regulation16. Waiting period, interpersonal relationships, negative self-concept, narrative exposure therapy18. Waiting period, interpersonal relationships, narrative exposure therapy, negative self-concept19. Waiting period, narrative exposure therapy, emotion regulation, negative self-concept2. Waiting period, emotion regulation, negative self-concept, narrative exposure therapy21. Waiting period, narrative exposure therapy, negative self-concept, emotion regulation22. Waiting period, narrative exposure therapy, negative self-concept, interpersonal relationships24. Waiting period, narrative exposure therapy, interpersonal relationships, negative self-concept25. Emotion regulation, negative self-concept, interpersonal relationships, waiting period26. Emotion regulation, negative self-concept, narrative exposure therapy, waiting period27. Emotion regulation, interpersonal relationships, negative self-concept, waiting period29. Emotion regulation, narrative exposure therapy, negative self-concept, waiting period3. Waiting period, emotion regulation, interpersonal relationships, negative self-concept31. Negative self-concept, emotion regulation, interpersonal relationships, waiting period32. Negative self-concept, emotion regulation, narrative exposure therapy, waiting period33. Negative self-concept, interpersonal relationships, emotion regulation, waiting period34. Negative self-concept, interpersonal relationships, narrative exposure therapy, waiting period35. Negative self-concept, narrative exposure therapy, emotion regulation, waiting period36. Negative self-concept, narrative exposure therapy, interpersonal relationships, waiting period37. Interpersonal relationships, emotion regulation, negative self-concept, waiting period39. Interpersonal relationships, negative self-concept, emotion regulation, waiting period40. Interpersonal relationships, negative self-concept, narrative exposure therapy, waiting period42. Interpersonal relationships, narrative exposure therapy, negative self-concept, waiting period43. Narrative exposure therapy, emotion regulation, negative self-concept, waiting period45. Narrative exposure therapy, negative self-concept, emotion regulation, waiting period46. Narrative exposure therapy, negative self-concept, interpersonal relationships, waiting period48. Narrative exposure therapy, interpersonal relationships, negative self-concept, waiting period5. Waiting period, emotion regulation, narrative exposure therapy, negative self-concept7. Waiting period, negative self-concept, emotion regulation, interpersonal relationships8. Waiting period, negative self-concept, emotion regulation, narrative exposure therapy9. Waiting period, negative self-concept, interpersonal relationships, emotion regulation

Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)BEHAVIORAL

ESTAIR is a psychotherapeutic manual for the treatment of CPTSD. The manual was adapted to the target population. It contains 24 sessions which are organised in four modules, including a module about interpersonal relationships. This module includes exercises to understand relationship patterns, increasing assertiveness, practicing assertiveness, and managing power.

1. Waiting period, emotion regulation, negative self-concept, interpersonal relationships10. Waiting period, negative self-concept, interpersonal relationships, narrative exposure therapy12. Waiting period, negative self-concept, narrative exposure therapy, interpersonal relationships13. Waiting period, interpersonal relationships, emotion regulation, negative self-concept14. Waiting period, interpersonal relationships, emotion regulation, narrative exposure therapy15. Waiting period, interpersonal relationships, negative self-concept, emotion regulation16. Waiting period, interpersonal relationships, negative self-concept, narrative exposure therapy17. Waiting period, interpersonal relationships, narrative exposure therapy, emotion regulation18. Waiting period, interpersonal relationships, narrative exposure therapy, negative self-concept20. Waiting period, narrative exposure therapy, emotion regulation, interpersonal relationships22. Waiting period, narrative exposure therapy, negative self-concept, interpersonal relationships23. Waiting period, narrative exposure therapy, interpersonal relationships, emotion regulation24. Waiting period, narrative exposure therapy, interpersonal relationships, negative self-concept25. Emotion regulation, negative self-concept, interpersonal relationships, waiting period27. Emotion regulation, interpersonal relationships, negative self-concept, waiting period28. Emotion regulation, interpersonal relationships, narrative exposure therapy, waiting period3. Waiting period, emotion regulation, interpersonal relationships, negative self-concept30. Emotion regulation, narrative exposure therapy, interpersonal relationships, waiting period31. Negative self-concept, emotion regulation, interpersonal relationships, waiting period33. Negative self-concept, interpersonal relationships, emotion regulation, waiting period34. Negative self-concept, interpersonal relationships, narrative exposure therapy, waiting period36. Negative self-concept, narrative exposure therapy, interpersonal relationships, waiting period37. Interpersonal relationships, emotion regulation, negative self-concept, waiting period38. Interpersonal relationships, emotion regulation, narrative exposure therapy, waiting period39. Interpersonal relationships, negative self-concept, emotion regulation, waiting period4. Waiting period, emotion regulation, interpersonal relationships, narrative exposure therapy40. Interpersonal relationships, negative self-concept, narrative exposure therapy, waiting period41. Interpersonal relationships, narrative exposure therapy, emotion regulation, waiting period42. Interpersonal relationships, narrative exposure therapy, negative self-concept, waiting period44. Narrative exposure therapy, emotion regulation, interpersonal relationships, waiting period46. Narrative exposure therapy, negative self-concept, interpersonal relationships, waiting period47. Narrative exposure therapy, interpersonal relationships, emotion regulation, waiting period48. Narrative exposure therapy, interpersonal relationships, negative self-concept, waiting period6. Waiting period, emotion regulation, narrative exposure therapy, interpersonal relationships7. Waiting period, negative self-concept, emotion regulation, interpersonal relationships9. Waiting period, negative self-concept, interpersonal relationships, emotion regulation

Narrative exposure therapy module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)BEHAVIORAL

ESTAIR is a psychotherapeutic manual for the treatment of CPTSD. It contains 24 sessions which are organised in four modules. The manual was adapted to the target population. In this context, the module "modified prolonged exposure" was replaced with Narrative Exposure Therapy (NET). NET is a standardised approach for the treatment of PTSD that has been tested across diverse social and cultural contexts. In this intervention, patients and therapists elaborate together a chronological timeline (called "the lifeline") of patient's life and the traumatic events, using a rope, stones for traumatic events, and flowers for positive events. Thereafter, the traumatic events are discussed in detail, one in each session. At the end of each session, patients receive a written form of these narrations, co-signed by patient and the therapist.

10. Waiting period, negative self-concept, interpersonal relationships, narrative exposure therapy11. Waiting period, negative self-concept, narrative exposure therapy, emotion regulation12. Waiting period, negative self-concept, narrative exposure therapy, interpersonal relationships14. Waiting period, interpersonal relationships, emotion regulation, narrative exposure therapy16. Waiting period, interpersonal relationships, negative self-concept, narrative exposure therapy17. Waiting period, interpersonal relationships, narrative exposure therapy, emotion regulation18. Waiting period, interpersonal relationships, narrative exposure therapy, negative self-concept19. Waiting period, narrative exposure therapy, emotion regulation, negative self-concept2. Waiting period, emotion regulation, negative self-concept, narrative exposure therapy20. Waiting period, narrative exposure therapy, emotion regulation, interpersonal relationships21. Waiting period, narrative exposure therapy, negative self-concept, emotion regulation22. Waiting period, narrative exposure therapy, negative self-concept, interpersonal relationships23. Waiting period, narrative exposure therapy, interpersonal relationships, emotion regulation24. Waiting period, narrative exposure therapy, interpersonal relationships, negative self-concept26. Emotion regulation, negative self-concept, narrative exposure therapy, waiting period28. Emotion regulation, interpersonal relationships, narrative exposure therapy, waiting period29. Emotion regulation, narrative exposure therapy, negative self-concept, waiting period30. Emotion regulation, narrative exposure therapy, interpersonal relationships, waiting period32. Negative self-concept, emotion regulation, narrative exposure therapy, waiting period34. Negative self-concept, interpersonal relationships, narrative exposure therapy, waiting period35. Negative self-concept, narrative exposure therapy, emotion regulation, waiting period36. Negative self-concept, narrative exposure therapy, interpersonal relationships, waiting period38. Interpersonal relationships, emotion regulation, narrative exposure therapy, waiting period4. Waiting period, emotion regulation, interpersonal relationships, narrative exposure therapy40. Interpersonal relationships, negative self-concept, narrative exposure therapy, waiting period41. Interpersonal relationships, narrative exposure therapy, emotion regulation, waiting period42. Interpersonal relationships, narrative exposure therapy, negative self-concept, waiting period43. Narrative exposure therapy, emotion regulation, negative self-concept, waiting period44. Narrative exposure therapy, emotion regulation, interpersonal relationships, waiting period45. Narrative exposure therapy, negative self-concept, emotion regulation, waiting period46. Narrative exposure therapy, negative self-concept, interpersonal relationships, waiting period47. Narrative exposure therapy, interpersonal relationships, emotion regulation, waiting period48. Narrative exposure therapy, interpersonal relationships, negative self-concept, waiting period5. Waiting period, emotion regulation, narrative exposure therapy, negative self-concept6. Waiting period, emotion regulation, narrative exposure therapy, interpersonal relationships8. Waiting period, negative self-concept, emotion regulation, narrative exposure therapy

Eligibility Criteria

Age17 Years+

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

Informed consent signature
Refugees and asylum seekers with a valid residence permit (N, F, B, or C status)
Speaking Arabic, Farsi/Dari, Pashtu, Kurdish (different dialects), or Turkish
A psychotherapy is indicated and was prescribed
Participated to part 1 of the study and was diagnosed with CPTSD on the basis of the standard International Trauma Interview and the Socio-cultural and structural addendum (SCSA). The diagnosis is done based on the clinical judgement by the local therapist.

You may not qualify if:

Acute psychosis
Imminent risk of suicide
Severe alcohol and/or substance abuse
Being enrolled in another psychotherapy
Inability to follow study procedures (i.e., cognitive impairment)
Inability to give informed consent
Known pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Eva Heimlead

Study Sites (7)

Centra

Hamburg, Hamburg, 20097, Germany

NOT YET RECRUITING

Psychiatrie Basel-Land

Liestal, Basel-Landschaft, 4410, Switzerland

RECRUITING

Psy4Asyl

Aarau, Canton of Aargau, 5000, Switzerland

RECRUITING

UPK Transkulturelle Ambulanz

Basel, Canton of Basel-City, 4051, Switzerland

RECRUITING

SRK Ambulatorium für Folter- und Kriegsopfer

Wabern, Canton of Bern, 3084, Switzerland

NOT YET RECRUITING

Appartenances - CPM Lausanne

Lausanne, Canton of Vaud, 1003, Switzerland

NOT YET RECRUITING

Appartenances - CPM Yverdon-les-Bains

Yverdon-les-Bains, Canton of Vaud, 1400, Switzerland

NOT YET RECRUITING

Related Publications (1)

Heim E, Karatzias T, Maercker A. Cultural concepts of distress and complex PTSD: Future directions for research and treatment. Clin Psychol Rev. 2022 Apr;93:102143. doi: 10.1016/j.cpr.2022.102143. Epub 2022 Mar 7.
PMID: 35313215BACKGROUND

Central Study Contacts

Eva Heim

CONTACT

+41 21 692 31 75 eva.heim@unil.ch

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: SINGLE
Who Masked: OUTCOMES ASSESSOR
Masking Details: Independent assessors are blinded to the intervention compoments (i.e., module or waiting) participants have received.
Purpose: TREATMENT
Intervention Model: FACTORIAL
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Associate professor

Study Record Dates

First Submitted

June 3, 2025

First Posted

June 11, 2025

Study Start

January 21, 2026

Primary Completion (Estimated)

December 1, 2030

Study Completion (Estimated)

December 1, 2030

Last Updated

January 27, 2026

Record last verified: 2026-01

Locations

DE(1)CH(6)

Brief Summary

Trial Health

Trial Health Score

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (5)

Study Arms (48)

1. Waiting period, emotion regulation, negative self-concept, interpersonal relationships

2. Waiting period, emotion regulation, negative self-concept, narrative exposure therapy

3. Waiting period, emotion regulation, interpersonal relationships, negative self-concept

4. Waiting period, emotion regulation, interpersonal relationships, narrative exposure therapy

5. Waiting period, emotion regulation, narrative exposure therapy, negative self-concept

6. Waiting period, emotion regulation, narrative exposure therapy, interpersonal relationships

7. Waiting period, negative self-concept, emotion regulation, interpersonal relationships

8. Waiting period, negative self-concept, emotion regulation, narrative exposure therapy

9. Waiting period, negative self-concept, interpersonal relationships, emotion regulation

10. Waiting period, negative self-concept, interpersonal relationships, narrative exposure therapy

11. Waiting period, negative self-concept, narrative exposure therapy, emotion regulation

12. Waiting period, negative self-concept, narrative exposure therapy, interpersonal relationships

13. Waiting period, interpersonal relationships, emotion regulation, negative self-concept

14. Waiting period, interpersonal relationships, emotion regulation, narrative exposure therapy

15. Waiting period, interpersonal relationships, negative self-concept, emotion regulation

16. Waiting period, interpersonal relationships, negative self-concept, narrative exposure therapy

17. Waiting period, interpersonal relationships, narrative exposure therapy, emotion regulation

18. Waiting period, interpersonal relationships, narrative exposure therapy, negative self-concept

19. Waiting period, narrative exposure therapy, emotion regulation, negative self-concept

20. Waiting period, narrative exposure therapy, emotion regulation, interpersonal relationships

21. Waiting period, narrative exposure therapy, negative self-concept, emotion regulation

22. Waiting period, narrative exposure therapy, negative self-concept, interpersonal relationships

23. Waiting period, narrative exposure therapy, interpersonal relationships, emotion regulation

24. Waiting period, narrative exposure therapy, interpersonal relationships, negative self-concept

25. Emotion regulation, negative self-concept, interpersonal relationships, waiting period

26. Emotion regulation, negative self-concept, narrative exposure therapy, waiting period

27. Emotion regulation, interpersonal relationships, negative self-concept, waiting period

28. Emotion regulation, interpersonal relationships, narrative exposure therapy, waiting period

29. Emotion regulation, narrative exposure therapy, negative self-concept, waiting period

30. Emotion regulation, narrative exposure therapy, interpersonal relationships, waiting period

31. Negative self-concept, emotion regulation, interpersonal relationships, waiting period

32. Negative self-concept, emotion regulation, narrative exposure therapy, waiting period

33. Negative self-concept, interpersonal relationships, emotion regulation, waiting period

34. Negative self-concept, interpersonal relationships, narrative exposure therapy, waiting period

35. Negative self-concept, narrative exposure therapy, emotion regulation, waiting period

36. Negative self-concept, narrative exposure therapy, interpersonal relationships, waiting period

37. Interpersonal relationships, emotion regulation, negative self-concept, waiting period

38. Interpersonal relationships, emotion regulation, narrative exposure therapy, waiting period

39. Interpersonal relationships, negative self-concept, emotion regulation, waiting period

40. Interpersonal relationships, negative self-concept, narrative exposure therapy, waiting period

41. Interpersonal relationships, narrative exposure therapy, emotion regulation, waiting period

42. Interpersonal relationships, narrative exposure therapy, negative self-concept, waiting period

43. Narrative exposure therapy, emotion regulation, negative self-concept, waiting period

44. Narrative exposure therapy, emotion regulation, interpersonal relationships, waiting period

45. Narrative exposure therapy, negative self-concept, emotion regulation, waiting period

46. Narrative exposure therapy, negative self-concept, interpersonal relationships, waiting period

47. Narrative exposure therapy, interpersonal relationships, emotion regulation, waiting period

48. Narrative exposure therapy, interpersonal relationships, negative self-concept, waiting period

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (7)

Related Publications (1)

Related Links

Central Study Contacts

Study Design

Study Record Dates

Locations