Diagnosis of Sarcopenia in Older Adults

NCT07011030 | Completed

• 1 other identifier: 25-PP-04
• Study Type: interventional
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Sarcopenia is defined as the loss of muscle strength and mass associated with aging and is one of the main causes of frailty in older people, and therefore of their ability to age gracefully. Given the aging of the French population, the diagnosis and management of this condition is a major public health issue and, in this context, it is therefore necessary to be able to quickly assess people's skeletal muscle mass. In its recommendations, French National Authority for Health recommends the use osteodensitometry and bioimpedance analysis (BIA) to assess skeletal muscle mass in the limbs for the purpose of diagnosing sarcopenia. Traditionally, BIA assessment is performed while lying down using adhesive electrodes placed on the hands and feet. The Biody XpertZM3 is a BIA device that allows seated measurement using integrated electrodes, enabling skeletal muscle mass to be assessed by bioimpedance analysis without the use of adhesive electrodes. However, the measurement position could alter the impedances measured and therefore the results obtained compared to other devices on the market as well as osteodensitometer

Conditions

Sarcopenia

Keywords

sarcopenia; elderly; bioimpedance analysis; osteodensitometry

Outcome Measures

Primary Outcomes (1)

• Appendicular skeletal muscle mass

  Comparison of skeletal muscle mass of the limbs (in kg) obtained by bioimpedance analysis using integrated electrodes and using osteodensitometry

  day 0

Study Arms (1)

Skeletal muscle mass measurement

EXPERIMENTAL

Patients will undergo a: * Bioimpedance analysis with the Biody XpertZM 3 (bioimpedance device with integrated electrodes ) * Osteodensitometer analysis with the SRATOS DR

Other: Measure of skeletal muscle mass

Interventions

Measure of skeletal muscle mass OTHER

Bioimpedance analysis with integrated electrodes and osteodensitometry examination

Skeletal muscle mass measurement

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Men or women aged 60 or over already receiving care at the Day Hospital of the Rehabilitation, Independence and Aging Center or the Frailty Platform of the Rehabilitation, Independence and Aging Center.
• Patients affiliated with or covered by a social security system.
• Patients who have signed an informed consent form in advance.

You may not qualify if:

• Vulnerable persons as defined in Articles L1121-5 to -8
• People with pacemakers, implantable defibrillators, or other electronic medical devices
• Musculoskeletal disorders that prevent bioimpedance measurement in a seated position
• Any condition of fluid retention or dehydration
• Absence of a measurement site (muscle resection or amputation)

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

Study Sites (1)

CHU de Nice

Nice, Alpes-Maritimes, 06000, France

Location

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Officials

• Frédéric CHORIN, PhD

  Centre Hospitalier Universitaire de Nice

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 30, 2025
• First Posted: June 8, 2025
• Study Start: September 23, 2025
• Primary Completion: December 4, 2025
• Study Completion: December 4, 2025
• Last Updated: December 16, 2025

Record last verified: 2025-12

Locations

FR (1)