Development and Testing of a Patient-facing Educational Tool About Liver Cancer Prevention

NCT07010315 | Recruiting

• 2 other identifiers: 2025-0299NCI-2025-03535
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

To develop and test liver cancer prevention educational material.

Conditions

Liver Cancer

Keywords

Liver cancer; Liver disease; Fibrosis; Cirrhosis

Outcome Measures

Primary Outcomes (2)

• Cognitive Testing

  Participant comprehension will be measured qualitatively through cognitive testing. In cognitive testing interviews, participants are asked to "think aloud" as they review and react to new information. Participants will be presented with the storyboard (mock-up) versions of the content and asked to describe in their own words what the information means to them. Cognitive interviews may include questions about content such as length, clarity of the language, and helpfulness of the educational material. A trained research team member will ask probing questions throughout interviews as needed. Based on patient feedback, modifications will be made iteratively to the content to ensure the content is understood and interpreted as intended. There is no post-survey for cognitive testing.

  Up to 1.5 hours

• Usability Testing

  Usability will be measured qualitatively using a Usability Interview Guide. Usability will also be measured using the System Usability Scale. Acceptability will be measured with the Ottawa Acceptability Measures. Knowledge will be measured pre- and post- session using knowledge questions developed by the investigators and refined during cognitive testing.

  Up to 1.5 hours

Study Arms (2)

Cognitive Interviews (English and Spanish)

Participants that agree to this part of the study will be asked to view patient education materials about liver cancer, complete a demographic survey, and do an interview one-on-one either online via Zoom, over the phone, or in person at HOPE Clinic.

Behavioral: Cognitive Testing

Usability Testing (English and Spanish)

Participants will be asked to complete a pre-survey, navigate a liver cancer education website, provide their feedback and impressions, and complete a post- survey.

Behavioral: Usability Testing

Interventions

Usability Testing BEHAVIORAL

Given by surveys and one-on-one interview.

Usability Testing (English and Spanish)

Cognitive Testing BEHAVIORAL

Given by Survey and one-on one interviews

Cognitive Interviews (English and Spanish)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants at HOPE Clinic

You may qualify if:

• At least 18 years old
• Participants at the HOPE Clinic
• Able to speak and read either English or Spanish
• For usability testing: Able to use and navigate websites on own smart phone or study computer

You may not qualify if:

• Has been diagnosed with liver cancer
• Cannot provide consent or otherwise participate in research activities (e.g. vision or hearing impairment)

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead
• Cancer Prevention Research Institute of Texas: collaborator

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

• MD Anderson Cancer Center

MeSH Terms

Conditions

Liver Neoplasms; Liver Diseases; Fibrosis

Interventions

Neuropsychological Tests; User-Centered Design

Condition Hierarchy (Ancestors)

Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Psychological Tests; Behavioral Disciplines and Activities; Equipment Design; Investigative Techniques; Universal Design; Engineering; Technology, Industry, and Agriculture

Study Officials

• Jessica Hwang, MD, MPH

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jessica Hwang, MD, MPH

CONTACT

(346) 720-7352; jphwang@mdanderson.org

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 9, 2025
• First Posted: June 8, 2025
• Study Start: May 1, 2025
• Primary Completion: April 30, 2026
• Study Completion (Estimated): April 30, 2027
• Last Updated: March 4, 2026

Record last verified: 2026-03

Locations

US (1)