Effectiveness of Wrist Extensor Strength Training With Blood Flow Restriction on Lateral Elbow Tendinopathy

NCT07007455 | Completed DMC

• 1 other identifier: MUR
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 2

Brief Summary

Repetitive and aggressive injuries to the elbow joint in sports often cause lateral elbow tendinitis (LET). In many clinical settings, therapists follow conventional methods according to their treatment protocols; however, complete rehabilitation is not always implemented. Without adequate care, elbow tendinitis can lead to chronic and recurring elbow injuries. Although many treatments are available, Blood flow restriction training (BFR) is a valuable option for exercise in cases where high-intensity training is too painful or contraindicated. In musculoskeletal disorders, it has been shown to induce hypoalgesia, and positive effects, such as improved muscle strength, growth, and tendon adaptations, have been demonstrated in healthy individuals.

Conditions

Lateral Epicondylitis (Tennis Elbow); Elbow Pain; Lateral Elbow Tendinopathy; Extensor Carpi Radialis Brevis (ECRB)

Keywords

Wrist extensor strength training; lateral epicondylitis; Tennis elbow; elbow pain

Outcome Measures

Primary Outcomes (2)

• pressure pain thresholds (PPTs).

  before and after intervention.

  six weeks

• pain-free grip strength test

  before and after intervention.

  six weeks

Secondary Outcomes (1)

• Borg 6-20 scale

  six weeks

Study Arms (2)

Experimental Group: wrist extensor strength training with BFR.

EXPERIMENTAL

Experimental Group: Participants will undergo wrist extensor strength training with blood flow restriction (BFR).

Behavioral: wrist extensor strength training with BFR.

Control Group: Wrist extensor strength training without BFR.

ACTIVE COMPARATOR

Control Group: Participants will undergo the same wrist extensor strength training without blood flow restriction (BFR).

Behavioral: wrist extensor strength training without BFR.

Interventions

wrist extensor strength training with BFR. BEHAVIORAL

Wrist extensor strength training without BFR.

Also known as: Wrist extensor strength training without BFR.

Experimental Group: wrist extensor strength training with BFR.

wrist extensor strength training without BFR. BEHAVIORAL

wrist extensor strength training without BFR.

Control Group: Wrist extensor strength training without BFR.

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both Male and female, aged between 18 to 45 years old.
• Subjects with a positive test of lateral epicondylitis, which will be determined based on physical therapy assessment procedures.
• The presence of tenderness over the lateral epicondyle.positive Cozen's and Mill's tests.
• Pain on grasping.
• Pain on passive flexion of the wrist with elbow extension.
• Pain with resisted wrist extension.
• Show decreased muscle strength and functional ability.

You may not qualify if:

• Patients with shoulder tendinopathy, cervical radiculopathy, and rheumatoid arthritis.
• Presences of sensory and motor impairment of the upper extremities
• History of cardiovascular disease
• History of trauma and surgery on the elbow
• Having a history of malignancy and peripheral vascular disorders.

Sponsors & Collaborators

• Majmaah University: lead

Study Sites (2)

Health Rehabiltation Center

Al Majma'ah, Al Riyadh, 11952, Saudi Arabia

Location

Majmaah University

Al Majma'ah, Al-Riyadh, Majmaah University, Saudi Arabia

Location

MeSH Terms

Conditions

Tennis Elbow

Condition Hierarchy (Ancestors)

Elbow Tendinopathy; Tendinopathy; Muscular Diseases; Musculoskeletal Diseases; Elbow Injuries; Arm Injuries; Wounds and Injuries; Tendon Injuries

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants were randomly assigned to the experimental group (WEST-BFR) and the control group (WEST without BFR).
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: This study will be a randomized controlled trial aimed at evaluating the effectiveness of wrist extensor strength training with blood flow restriction (BFR) in reducing pain, improving grip strength, and enhancing functional performance in individuals with lateral elbow tendinopathy.

Study Record Dates

• First Submitted: May 28, 2025
• First Posted: June 5, 2025
• Study Start: February 15, 2025
• Primary Completion: May 15, 2025
• Study Completion: May 25, 2025
• Last Updated: December 8, 2025

Record last verified: 2025-01

Locations

SA (2)