Comparison of the Effectiveness of Mulligan Mobilization and Myofascial Release Technique in Patients With Lateral Epicondylitis

NCT06965985 | Recruiting

• 1 other identifier: KonyaBeyhekimTRH2023/4512
• Study Type: interventional
• Target: 114
• Locations: 1 country
• Sites: 1

Brief Summary

Lateral epicondylitis (LE), recognized as one of the most prevalent causes of elbow pain, has an estimated incidence ranging from 1% to 3%. It most commonly presents in individuals between the ages of 40 and 50 and tends to affect the dominant limb more frequently. In the adult population, LE is the leading cause of lateral elbow pain. To date, more than 40 different treatment modalities have been described for the management of LE, primarily aiming to alleviate pain and enhance functional outcomes. However, a universally accepted standard treatment has yet to be established. The objective of this thesis is to compare the clinical effectiveness of the Mulligan mobilization technique and the myofascial release technique-both commonly utilized in the treatment of LE-through a prospective clinical study.

Conditions

Lateral Epicondylitis (Tennis Elbow)

Keywords

Lateral Epicondylitis; Mobilization Techniques; Myofascial Release; Exercise Therapy

Outcome Measures

Primary Outcomes (2)

• VAS pain (0-10)

  0 no pain; 10 unbearable/max. pain

  baseline, week 4 and week 8

• grip strength

  using a Jamar® dynamometer (in kilograms)

  baseline, week 4 and week 8

Secondary Outcomes (4)

• The Disabilities of the Arm, Shoulder, and Hand (DASH)

  baseline, week 4 and week 8

• Patient-Rated Tennis Elbow Evaluation Questionnaire (PRTEE)

  baseline, week 4 and week 8

• The Short Form-36 (SF-36) quality of life index

  baseline, week 4 and week 8

• Patient satisfaction/benefit scale (The Roles and Maudsley score)

  week 4 and week 8

Study Arms (3)

Mulligan mobilization techniqu

EXPERIMENTAL

Will receive Mulligan mobilization therapy three times per week for four weeks (a total of 12 sessions), along with a home exercise program

Other: Mulligan mobilization therapy

Myofascial release therapy

EXPERIMENTAL

will receive myofascial release therapy three times per week for four weeks (a total of 12 sessions), in combination with a home exercise program.

Other: Myofascial release therapy

Exercise Therapy

ACTIVE COMPARATOR

Will follow only the home exercise program, three times per week for four weeks (12 sessions total).

Other: Exercise Therapy

Interventions

Mulligan mobilization therapy OTHER

While the mobilization belt is placed around the patient's proximal forearm and looped over the therapist's shoulder, the distal humerus will be stabilized with one hand. A lateral glide will be applied to the forearm through the belt and maintained for approximately 5 to 10 seconds. The patient will perform repeated wrist extensions against the manual resistance provided by the therapist's hand. Once a pain-free wrist extension is achieved, the lateral glide will be released. A total of 6 repetitions will be performed with 15-second rest intervals between repetitions. This protocol will be applied three times per week for two weeks.

Mulligan mobilization techniqu

Myofascial release therapy OTHER

The patient will be placed in a supine position with the shoulder internally rotated, the elbow in pronation and approximately 15 degrees of flexion, and the palm resting flat on the table. The therapist will stand beside the table at the level of the patient, facing the patient's ipsilateral arm and shoulder. The treatment will be administered for 10 minutes, three sessions per week for two weeks. The therapist will begin the treatment from just proximal to the lateral epicondyle, on the humerus, and proceed distally along the path of the common extensor tendon to the extensor retinaculum of the wrist. Using the fingertips, the therapist will engage the periosteum and maintain contact as the technique continues along the common extensor tendon and further distally along the extensor retinaculum of the wrist.

Myofascial release therapy

Exercise Therapy OTHER

All patients will be provided with a home exercise program consisting of eccentric strengthening exercises targeting the wrist extensors, with resistance gradually increased each week. Patients will be instructed in strengthening exercises for the wrist extensors as well as forearm pronation and supination. The home program will consist of 3 sets of 10 repetitions per day. The exercises will be demonstrated in person by the physician, and each patient will receive a printed handout detailing how to perform the exercises. During weekly treatment sessions and after the treatment period, patients will be contacted by phone to assess adherence to the exercise program and to reinforce the importance of compliance. Patients with exercise compliance below 75-80% will be excluded from the study.

Exercise Therapy

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged between 18 and 65 years
• Diagnosed with unilateral lateral epicondylitis (LE)

You may not qualify if:

• Younger than 18 or older than 65 years
• Communication difficulties
• History of injection, surgery, or physical therapy in the elbow region within the past 6 months
• Pain originating from the cervical spine (e.g., radiculopathy, spinal stenosis), shoulder problems, or other elbow pathologies unrelated to LE
• History of elbow osteoarthritis or previous elbow fracture
• History of polyneuropathy
• Uncontrolled systemic diseases (e.g., cardiovascular, pulmonary, hepatic, renal, hematologic disorders)
• Uncontrolled systemic endocrine disorders (e.g., diabetes mellitus, hyperthyroidism)
• History of major psychiatric disorders
• History of rheumatic diseases such as fibromyalgia, polymyalgia rheumatica, ankylosing spondylitis, or rheumatoid arthritis
• Presence of bleeding disorders or use of anticoagulant medications
• Neurological deficits
• Posterior interosseous nerve (PIN) syndrome
• Current or past use of wrist resting splints or elbow braces

Sponsors & Collaborators

• Konya Beyhekim Training and Research Hospital: lead

Study Sites (1)

Konya Beyhekim Eğitim ve Araştırma Hastanesi

Konya, Selçuklu, 42060, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Tennis Elbow

Interventions

Myofascial Release Therapy; Exercise Therapy

Condition Hierarchy (Ancestors)

Elbow Tendinopathy; Tendinopathy; Muscular Diseases; Musculoskeletal Diseases; Elbow Injuries; Arm Injuries; Wounds and Injuries; Tendon Injuries

Intervention Hierarchy (Ancestors)

Massage; Therapy, Soft Tissue; Musculoskeletal Manipulations; Complementary Therapies; Therapeutics; Physical Therapy Modalities; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care

Central Study Contacts

Cansu Ertuğrul

CONTACT

+905373328271; cansuertugrl@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 2, 2025
• First Posted: May 11, 2025
• Study Start: January 1, 2025
• Primary Completion: April 1, 2026
• Study Completion: April 1, 2026
• Last Updated: May 11, 2025

Record last verified: 2025-05

Locations

TU (1)