Preoperative Analgesia: The Effectiveness of the PENG Block in Patients With Hip Fractures

NCT07003633 | Not Yet Recruiting

• 1 other identifier: E-43012747-050.04-463726-205
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim is to provide effective preoperative analgesia in patients undergoing surgical procedures due to hip fractures by administering a pericapsular nerve group (PENG) block under ultrasound guidance. This approach seeks to increase patient satisfaction, reduce analgesic requirements, enable earlier discharge, and decrease morbidity and mortality.

Conditions

Hip Fracture Surgeries

Keywords

Analgesia; PENG block; Hip Fracture

Outcome Measures

Primary Outcomes (1)

• Preoperative Pain Scores and Opioid Consumption

  Preoperative pain of patients will be assessed with NRS (Numeric Raitng Scale) which ranges from 0 (no pain) to 10 (the most severe pain imaginable).

  24 hours preoperatively

Secondary Outcomes (3)

• Discharge Time

  From surgery to discharge up to 30 days

• Postoperative Mortality and Morbidity

  30 days after surgery

• Opioid Consumption

  24 hours preoperatively

Study Arms (2)

Group PENG

EXPERIMENTAL

Group PENG will involve the patients who will be performed PENG block 24 hours before surgery.

Procedure: PENG block with 0.25% bupivacaine guided by ultrasound.

Group Control

NO INTERVENTION

Group Control will involve the patients who will not be performed PENG block preoperatively.

Interventions

PENG block with 0.25% bupivacaine guided by ultrasound. PROCEDURE

PENG (Pericapsular nerve block) is a peripheral nerve block which is performed for patients with hip fractures aimed to prevent preoperative and postoperative pain. It is performed under sterile conditions under ultrasound guideance.

Group PENG

Eligibility Criteria

• Age: 45 Years - 95 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients undergoing hip farcture surgery

You may not qualify if:

• Chronic analgesics consumption
• Patients contraindicated for neuraxial anesthesia
• Alcohol and drug addiction
• Allergies to local anesthetics and opioids
• Patients who refuses to participate in the study

Sponsors & Collaborators

• Sakarya University: lead

Study Sites (1)

Sakarya Universtiy Training and Research Hospital

Sakarya, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Agnosia; Hip Fractures

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries

Central Study Contacts

Alim Miniksar, M.D.

CONTACT

+905069499002; alimminiksar@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: The patients will be randomized to their rescpective groups with closed envelope method.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiology and Reanimation Resident, M.D.

Study Record Dates

• First Submitted: May 15, 2025
• First Posted: June 4, 2025
• Study Start: June 1, 2025
• Primary Completion: January 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: June 4, 2025

Record last verified: 2025-05

Locations

TU (1)