The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters

NCT07002307 | Completed

• 1 other identifier: Uuthuyo
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose. The main questions it aims to answer are: Does honey-sweetened black tea, green tea, and coffee, respectively, have the ability to influence blood pressure, heart rate, or blood glucose level? Research will compare honey-sweetened black tea, green tea, and coffee to a placebo (warm water) to see if honey-sweetened black tea, green tea, and coffee work to reduce or increase blood pressure, heart rate, or blood glucose. Participants will: Take honey-sweetened black tea, green tea, and coffee, OR plain black tea, green tea, and coffee, OR warm water, one cup a day for 3 days The beverages will be taken at the Physiology laboratory, University of Uyo, and the participants will be observed for 60 minutes, during which their blood pressure, heart rate, and blood glucose level will be measured. This procedure will be repeated for the 3 days of study.

Conditions

Blood Pressure; Heart Rate; Blood Glucose

Keywords

Coffee; Honey-sweetened coffee; Black tea; Honey-sweetened black tea; Green Tea; Honey-sweetened green tea; Blood pressure; Heart rate; Blood glucose

Outcome Measures

Primary Outcomes (3)

• Blood pressure

  Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

• Heart rate

  Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

• Blood glucose

  Will be measured before consumption of the beverages and at 30 and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.

Secondary Outcomes (3)

• Age

  Will obtained during the eligibility process

• Height

  Will be measured on the first day of the experiment before the commencement of the experiment.

• Body weight

  Measurements will be taken over the course of the 3-day study prior to the commencement of the experiment each day.

Study Arms (7)

Control group

PLACEBO COMPARATOR

Will receive 250 mL of warm water

Other: Warm water at 35 oC

Coffee group

ACTIVE COMPARATOR

Will receive 2.25 g of coffee dissolved in 250 mL of hot water

Other: Coffee

Honey-sweetened coffee group

ACTIVE COMPARATOR

Will receive 2.25 g of coffee plus 20 mL of honey put in 250 mL of hot water

Other: Honey-sweetened coffee

Green tea group

ACTIVE COMPARATOR

Will receive 2 g of green tea infuse in 250 mL of hot water

Other: Green tea

Honey-sweetened green tea group

ACTIVE COMPARATOR

Will receive 2 g of green tea plus 250 mL of honey put in 250 mL of hot water

Other: Honey-sweetened green tea

Black tea group

ACTIVE COMPARATOR

Will receive 2 g of black tea infuse in 250 mL of hot water

Other: Black tea

Honey-sweetened black tea group

ACTIVE COMPARATOR

Will receive 2 g of black tea plus 20 mL of honey put in 250 mL of hot water

Other: Honey-sweetened black tea

Interventions

Warm water at 35 oC OTHER

The placebo for the control group

Control group

Coffee OTHER

Instant coffee, Nescafé Gold Blend, manufactured by Nestlé Coffee Brand, Nestlé Global

Coffee group

Honey-sweetened coffee OTHER

Instant coffee plus raw dark amber honey produced by Apis mellifera adansonii

Honey-sweetened coffee group

Green tea OTHER

Qualitea Natural Green Tea, packed by Qualitea Ceylon (PVT) LTD

Green tea group

Honey-sweetened green tea OTHER

Green tea plus honey

Honey-sweetened green tea group

Black tea OTHER

Lipton Yellow Label Black Tea

Black tea group

Honey-sweetened black tea OTHER

Black tea plus honey

Honey-sweetened black tea group

Eligibility Criteria

• Age: 18 Years - 26 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age between 18 and 26
• Non-habitual coffee and tea drinkers who consume coffee, green tea, or black tea 2-5 times in the last two months
• Non-allergic to coffee, green tea, black tea, or honey
• Absence of medication use
• Will refrain from ingesting energy drinks, carbonated beverages, caffeinated beverages, or food for 24 hours before the study and throughout the study periods
• Will not consume anything except water after 11 p.m. during the experimental days Will be available and cooperate throughout the study duration.

You may not qualify if:

• Presence of cardiovascular disorders, hypertension, or diabetes
• Blood pressure above 120/80 mmHg and random blood glucose above 125 mg/dL
• Alcohol intake
• Smoking
• Habitual coffee or tea drinker

Sponsors & Collaborators

• University of Uyo Teaching Hospital: lead

Study Sites (1)

Physiology laboratory, Physiology Department, Faculty of Basic Medical Sciences, University of Uyo

Uyo, Akwa Ibom State, 520003, Nigeria

Location

MeSH Terms

Interventions

Coffee; Tea

Intervention Hierarchy (Ancestors)

Plant Preparations; Biological Products; Complex Mixtures; Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Esther O Aluko

  University of Uyo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator (PI)

Study Record Dates

• First Submitted: May 23, 2025
• First Posted: June 3, 2025
• Study Start: October 17, 2023
• Primary Completion: October 19, 2023
• Study Completion: October 19, 2023
• Last Updated: June 15, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

NG (1)