NCT07001761

Brief Summary

Assessment of the effectiveness of ultrasonography in correlation to conventional imaging for the detection of the definite grading of knee osteoarthritis.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
1mo left

Started Apr 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress96%
Apr 2025May 2026

Study Start

First participant enrolled

April 7, 2025

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

May 21, 2025

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 3, 2025

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 25, 2026

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 25, 2026

Expected
Last Updated

June 3, 2025

Status Verified

May 1, 2025

Enrollment Period

1 year

First QC Date

May 21, 2025

Last Update Submit

May 31, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • The outcome for the study is to test the MUS score's ability to discern various degrees of knee OA, in comparison with plain radiography and the 'Knee injury and Osteoarthritis Outcome Score' (KOOS).

    6 months

Interventions

* The MSK Ultrasound (US) will be performed using a General Electric LOGIQ P9 unit / Toshiba Applio 500 unit using a 7-13 MHz linear array transducer. * Conventional Radio-graphic examination bi-plane weight-bearing semi-flexed (15) radiograms will be taken of the target knee; one in the posteroanterior view, and one in the lateral medial view

Eligibility Criteria

Age30 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

community sample

You may qualify if:

  • Age: above 30 years. Unilateral or bilateral knee joint affection. Symptomatic patient.

You may not qualify if:

  • Any female patient in the child bearing period presented with Chronic inflammatory joint disease as Rheumatoid arthritis, SLE. Systemic diseases: Renal failure. Significant joint trauma or surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sohag University hospitals

Sohag, Egypt

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

High-Energy Shock WavesX-Rays

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

Ultrasonic WavesSoundRadiation, NonionizingRadiationPhysical PhenomenaElectromagnetic RadiationElectromagnetic PhenomenaMagnetic PhenomenaRadiation, Ionizing

Central Study Contacts

Noha Mohammed Elaref

CONTACT

Mohammed Mahmoud Eldeeb

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
18 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident doctor at radiology department Sohag University

Study Record Dates

First Submitted

May 21, 2025

First Posted

June 3, 2025

Study Start

April 7, 2025

Primary Completion

April 25, 2026

Study Completion (Estimated)

May 25, 2026

Last Updated

June 3, 2025

Record last verified: 2025-05

Locations