Study of Rule-Based Algorithms in Anemia Management in Prevalent Hemodialysis Patients and Its Relation to Patients' Outcomes

NCT06996717 | Active Not Recruiting Phase 1

• 1 other identifier: MS 7/2024/2025
• Study Type: interventional
• Target: 145
• Locations: 1 country
• Sites: 1

Brief Summary

The study will assess role of rule based algorithm in anemia management in hemodialysis patients and its relation to patient's mortality

Conditions

Anemia in End Stage Renal Disease

Outcome Measures

Primary Outcomes (1)

• Increase the number of patients in the target Hb range

  This study will achieve better dosing of erythropoietin stimulating agents using rule based algorithms to correct anemia and avoid unnecessary extra doses of erythropoietin stimulating agents with their side effects

  6 months

Study Arms (1)

end stage renal disease patients

EXPERIMENTAL

management of different hemoglobin levels by erythropoietin stimulating agents according to expert opinion and according to algorithm

Drug: ESA

Interventions

ESA DRUG

anemia management algorithm will successfully increase the number of patients in the target hemoglobin range

end stage renal disease patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• patients on hemodialysis for more than six months patients undergoing hemodialysis three times per week each session for 4 hours patients with urea reduction ratio\>65% patients with transferrin saturation\>20%

You may not qualify if:

• patients with terminal illness or malignancy patients receiving hemodialysis from catheter or arteriovenous graft

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Hemodialysis Units in Ain Shams University Hospitals

Cairo, Egypt

Location

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2025
• First Posted: May 30, 2025
• Study Start: January 1, 2025
• Primary Completion: June 30, 2025
• Study Completion: June 30, 2025
• Last Updated: May 30, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)