Relaxation Music for Chronic Pain

NCT06993272 | Active Not Recruiting

• 1 other identifier: 5116
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic pain is a common complaint in inflammatory bowel disease (IBD). Compounding these concerns, opioid analgesics are frequently used to treat severe acute pain. An estimated 30% of chronic pain patients due to IBD report opioid use. Those who continue to use opioids can develop opioid misuse, and opioid misuse portends addiction and overdose so there is a need for better, non-addictive treatment options. Music interventions effectively reduce pain and pain-related symptomology. Meta-analytic results indicate listening to music can reduce acute and chronic pain. Music listening also decreases emotional distress from pain as well as the use of pain medication. Music interventions have demonstrated these positive effects on pain across a number of settings, including surgical, in-patient, and community settings. Importantly, due to the ubiquity of music - especially freely available online music - music interventions are easily accessible and highly scalable.

Conditions

IBS - Irritable Bowel Syndrome; IBD - Inflammatory Bowel Disease

Outcome Measures

Primary Outcomes (1)

• Pain, Enjoyment, General Activity Scale (PEG)

  Pain Intensity: Measure: The PEG scale will be used to assess the magnitude of pain sensations experienced by participants in the past week.

  Baseline and 4 weeks

Study Arms (4)

MIndful Jazz

EXPERIMENTAL

Participants in this group will watch an introduction to jazz appreciation and mindfulness training video, including the use of jazz for pain tolerance prior to the 4-week intervention. Participants in the Mindful Jazz Group will be informed that listening to music they are not comfortable with (i.e., jazz) can enhance long-term pain tolerance.

Behavioral: MIndful Jazz

Reggae Stereotypes

EXPERIMENTAL

Reggae Stereotype Group: Participants in this group will be told about he stereotype of reggae in making people more calm. They will listen to reggae music over the 4 weeks.

Behavioral: Reggae Stereotypes

Traditional Mindfulness

EXPERIMENTAL

Participants in this group will listen to a traditional mindfulness practice over the 4 weeks

Behavioral: Traditional Mindfulness

Pain Psychoeducation

ACTIVE COMPARATOR

Participants listen to the same playlist each week of the 4-weeks. It's an audio recording of the pain psychoeducation video they watch during training. Video: https://www.youtube.com/watch?v=azwEQXh5enA

Behavioral: Pain psychoeducation

Interventions

MIndful Jazz BEHAVIORAL

Mindful Jazz Group: Participants in this group will watch an introduction to jazz appreciation and mindfulness training video, including the use of jazz for pain tolerance prior to the 4-week intervention. Participants in the Mindful Jazz Group will be informed that listening to music they are not comfortable with (i.e., jazz) can enhance long-term pain tolerance.

MIndful Jazz

Reggae Stereotypes BEHAVIORAL

Reggae Stereotype Group: Participants in this group will be told about he stereotype of reggae in making people more calm. They will listen to reggae music over the 4 weeks.

Reggae Stereotypes

Traditional Mindfulness BEHAVIORAL

Participants will listen to a traditional mindfulness practice over the 4 weeks

Traditional Mindfulness

Pain psychoeducation BEHAVIORAL

Participants listen to an audio recording of the pain psychoeducation video they watch during training over the 4 weeks. Video: https://www.youtube.com/watch?v=azwEQXh5enA

Pain Psychoeducation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• or older
• Living in U.S.
• Have a pain rating related to IBS, Crohn's, or Colitis of five or greater in average pain on a 0-10 numeric rating scale in the preceding week
• Have had pain related to IBS, Crohn's, or Colitis for at least 3 months and for at least 15 days in the preceding 30 days
• GAD Score (Moderate to Severe Anxiety)

You may not qualify if:

• Are currently using or have used prescription opioids in the past 3 months
• Have a current cancer diagnosis
• In one of our prior music studies
• Have formal experience with mindfulness

Sponsors & Collaborators

• University of California, Irvine: lead

Study Sites (1)

University of California Irvine

Orange, California, 92868, United States

Location

MeSH Terms

Conditions

Irritable Bowel Syndrome; Inflammatory Bowel Diseases

Condition Hierarchy (Ancestors)

Colonic Diseases, Functional; Colonic Diseases; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Gastroenteritis

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: April 18, 2025
• First Posted: May 28, 2025
• Study Start: April 20, 2025
• Primary Completion: February 20, 2026
• Study Completion: March 1, 2026
• Last Updated: February 2, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)