Evaluation for Healing of Iatrogenic Perforation After Non Surgical Repair

NCT06991569 | Completed

• 1 other identifier: FDASU-REC 1117 Retrospective
• Study Type: observational
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this retrospective study is to evaluate the outcome of nonsurgical root perforation repair treated by specialized endodontist . The null hypothesis is: MTA can be used successfully as perforation repair material with high success rate subjects of the study were identified from patients who had received endodontic treatment with non-surgical root perforation repair by an endodontic specialist in his private practice

Conditions

Root Perforation at the Bifurcation Area; Strip Perforation; Lateral Perforation

Keywords

Root canal perforation; Endodontics; MTA; Perforation repair material

Outcome Measures

Primary Outcomes (1)

• Radiographic success in terms of Healing

  Healing outcome: the presence or absence of lesion and its size were obtained by analyzing CBCT of each case and classified into: Cases with complete resolution of lesion considered as "Healed", reduction of size considered as "Healing", and no size change or increase in lesion size considered as "Failure"

  7 years

Interventions

Non-surgical perforation repair PROCEDURE

Root perforation repair using MTA or other perforation repair material

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

subjects were identified from among patients treated by endodontic specialist in his private clinic at Cairo, Egypt

You may qualify if:

• patients who had undergone nonsurgical endodontic perforation repair

You may not qualify if:

• Teeth that revealed root fracture, inadequate remaining tooth structure, or severe periodontitis
• Teeth that had undergone surgical perforation repair

Sponsors & Collaborators

• Mohamed Salah Elwakeel: lead
• Ain Shams University: collaborator

Study Sites (1)

Advanced Endodontic clinic

Cairo, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant lecturer

Study Record Dates

• First Submitted: May 9, 2025
• First Posted: May 28, 2025
• Study Start: January 1, 2023
• Primary Completion: August 1, 2024
• Study Completion: August 1, 2024
• Last Updated: May 31, 2025

Record last verified: 2025-03

Locations

EG (1)