NCT06981208

Brief Summary

In this study, patients who are scheduled for breast reconstruction consultation will be randomized into the intervention group (ChatGPT-generated patient education regarding possible reconstruction options) or the control group (usual patient education). All patients will complete a survey following their in-person consultation to assess their experience and overall satisfaction with the consultation process. Additionally, participating surgeons will complete a separate survey to evaluate their consultation experience, satisfaction, and to assess the accuracy and clinical utility of the ChatGPT-generated patient education materials. The surveys are designed to gather information on patient characteristics, organizational health literacy according to Brega et al. Other survey questions have been designed to meet the outcomes of this study and have not been based on previously published surveys.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
410

participants targeted

Target at P75+ for not_applicable breast-cancer

Timeline
2mo left

Started Jun 2025

Shorter than P25 for not_applicable breast-cancer

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress86%
Jun 2025Jun 2026

First Submitted

Initial submission to the registry

May 12, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 20, 2025

Completed
14 days until next milestone

Study Start

First participant enrolled

June 3, 2025

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2026

Last Updated

June 10, 2025

Status Verified

June 1, 2025

Enrollment Period

1.1 years

First QC Date

May 12, 2025

Last Update Submit

June 5, 2025

Conditions

Keywords

Patient educationChatGPTBreast reconstruction

Outcome Measures

Primary Outcomes (1)

  • Patient perceived understanding of breast reconstruction

    The patient will choose an answer ranging from 0-100 (strongly disagree to strongly agree). The higher the score, the more perceived understanding the patient had.

    Pre-surgical consultation (day 1)

Secondary Outcomes (5)

  • Patient satisfaction with education regarding breast reconstruction

    Pre-surgical consultation (day 1)

  • Surgeon satisfaction with the consultation process

    Pre-surgical consultation (day 1)

  • Surgeon perception of patient preparedness

    Pre-surgical consultation (day 1)

  • Surgeon views on the efficiency of the consultation

    Pre-surgical consultation (day 1)

  • Surgeon overall experience with the consultation

    Pre-surgical consultation (day 1)

Study Arms (3)

ChatGPT-generated patient education

EXPERIMENTAL

* Pre-consultation ChatGPT patient education: The patients randomized into the ChatGPT education group will receive a ChatGPT patient education on paper prior to their consultation. The ChatGPT will write a patient-tailored education regarding possible reconstruction options. The patient will review this independently, without additional input or guidance from a research team member * Patient post-consultation survey: All patients will receive a survey after the planned in-person consultation with the plastic surgeon.

Other: ChatGPT-generated patient education

Usual education

ACTIVE COMPARATOR

\- Patients will not receive any additional information prior to their consultation.

Other: Usual patient education

Surgeons

NO INTERVENTION

* In order for the surgeon to be blinded to the study arm, all participants will have ChatGPT education created. Participating surgeons will review each patient education sheet prior to the consult and score the accuracy of the provided education sheet. The surgeon will proceed with the consultation as planned. The surgeon is blinded to the patient's study arm as they will be reviewing ChatGPT education for all patients. If any inaccuracies are identified in the patient education sheet, the surgeon will address this with the study team and have the errors fixed prior to providing to the patient. * The surgeon will receive a survey after each in-person consultation, covering patient experience, surgeon experience, and education material accuracy.

Interventions

This is created by entering the patient's age, medical history, social history, and case-specific details into Washington University ChatGPT Beta (HIPAA and FERPA compliant) by a study team member.

ChatGPT-generated patient education

Usual patient education will include description of breast reconstruction options, with further elaboration on which option are more suitable to the patient. This include also review of risk of complications and expected recovery after surgery.

Usual education

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Patient Eligibility Criteria: * Scheduled for initial preoperative breast reconstruction consultation following therapeutic or prophylactic mastectomy with a surgeon at Washington University School of Medicine. * At least 18 years of age. * Can speak and understand English. Surgeon Eligibility Criteria: * Routinely performs breast reconstruction surgery at Washington University School of Medicine. * At least 18 years of age. * Can speak and understand English. * Surgeon must not be a resident or fellow at time of enrollment.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Washington University School of Medicine

St Louis, Missouri, 63110, United States

RECRUITING

Related Links

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Saif M Badran, M.D., Ph.D., FRCS

    Washington University School of Medicine

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Saif M Badran, M.D., Ph.D., FRCS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
CARE PROVIDER
Masking Details
The surgeons will be blinded to the patient's randomization arm prior to the in-person consultation.
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2025

First Posted

May 20, 2025

Study Start

June 3, 2025

Primary Completion (Estimated)

June 30, 2026

Study Completion (Estimated)

June 30, 2026

Last Updated

June 10, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

Locations