Construction of Clinical Diagnostic Model for Pulmonary Hypertension

NCT06979011 | Completed

• 2 other identifiers: LY2025-122-BNSFC82270050
• Study Type: observational
• Target: 199
• Locations: 1 country
• Sites: 1

Brief Summary

Primary objective: To establish a non-invasive diagnostic model for pulmonary hypertension based on laboratory indicators and echocardiographic parameters. Secondary objectives: To investigate the correlations between laboratory test indicators and echocardiographic data, and to develop new parameters based on preliminary analysis to assist in the diagnosis of pulmonary hypertension

Conditions

Pulmonary Hypertension

Keywords

pulmonary hypertension; diagnosis; machine learning; heamodynamic status

Outcome Measures

Primary Outcomes (1)

• AUC

  the area under ROC curve

  from 1 Jan 2025 to 30 Apr 2025

Study Arms (1)

pulmonary hypertension

people with pulmonary hypertension

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with all types of PH

You may qualify if:

• Patients diagnosed with any subtype of pulmonary hypertension (PH) confirmed by right heart catheterization (RHC) between 2020 and 2025.
• No gender restrictions; age \>18 years.
• Availability of complete RHC records, transthoracic echocardiography (TTE), and laboratory test results (echocardiography and lab tests must be performed within one month before or after RHC).

You may not qualify if:

• Pulmonary veno-occlusive disease (PVOD)
• Active or history of malignancy (or Malignant tumors if referring to current cases)
• Hematologic disorders

Sponsors & Collaborators

• RenJi Hospital: lead

Study Sites (1)

Renji Hospital

Shanghai, Shanghai Municipality, China

Location

MeSH Terms

Conditions

Hypertension, Pulmonary; Disease

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Hypertension; Vascular Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 11, 2025
• First Posted: May 18, 2025
• Study Start: January 1, 2025
• Primary Completion: March 25, 2025
• Study Completion: April 30, 2025
• Last Updated: May 18, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)